{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:48:10Z","timestamp":1792176490548,"version":"4.4.0"},"reference-count":85,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,12,29]],"date-time":"2023-12-29T00:00:00Z","timestamp":1703808000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Geriatrics Gerontology Int"],"published-print":{"date-parts":[[2024,2]]},"abstract":"<jats:p>\n                    Sarcopenia has a significant impact on falls, physical function, activities of daily living, and quality of life in older adults, and its prevention and treatment are becoming increasingly important as the global population ages. In addition to primary age\u2010related sarcopenia, activity\u2010related sarcopenia, disease\u2010related sarcopenia, and nutrition\u2010related sarcopenia have been proposed as secondary sarcopenia. Polypharmacy and potentially inappropriate medication based on multiple diseases cause health problems in older patients. In some cases, drugs used for therapeutic or preventive purposes act on skeletal muscle as adverse drug reactions and induce sarcopenia. Although sarcopenia caused by these adverse drug reactions may be more common in older patients, in particular those taking many medications, drug\u2010related sarcopenia has not yet received much attention. This review summarizes drugs that may induce sarcopenia and emphasizes the importance of drug\u2010related sarcopenia as a secondary sarcopenia.\n                    <jats:bold>Geriatr Gerontol Int 2024; 24: 195\u2013203<\/jats:bold>\n                    .\n                  <\/jats:p>","DOI":"10.1111\/ggi.14770","type":"journal-article","created":{"date-parts":[[2023,12,30]],"date-time":"2023-12-30T02:44:30Z","timestamp":1703904270000},"page":"195-203","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":51,"title":["Drug\u2010related sarcopenia as a secondary sarcopenia"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6134-9578","authenticated-orcid":false,"given":"Masafumi","family":"Kuzuya","sequence":"first","affiliation":[{"name":"Meitetsu Hospital  Nagoya Japan"},{"name":"Professor Emeritus Nagoya University  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,12,29]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/50.5.1231"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afq034"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00002.2019"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/ggi.14616"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvac020"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2014.03.019"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0128398"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2014.2266"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/JES.0b013e31826c169e"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOL.0b013e32833c1edf"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/ggi.14646"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2021.04.054"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17051494"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-022-02942-7"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40266-016-0370-5"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.136101"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-020-00742-y"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2023.112060"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40266-023-01042-4"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells10081958"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/prp2.28"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/9368583"},{"key":"e_1_2_8_24_1","first-page":"136","article-title":"Insights into pathogenesis, nutritional and drug approach in sarcopenia: a systematic review","volume":"11","author":"Mellen RH","year":"2023","journal-title":"Biomedicine"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.3803\/EnM.2019.34.3.247"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2023.1203666"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2023.1220516"},{"key":"e_1_2_8_28_1","first-page":"905","article-title":"Chemotherapy\u2010induced molecular changes in skeletal muscle","volume":"11","author":"Pedrosa MB","year":"2023","journal-title":"Biomedicine"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11864-019-0691-9"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.24.9730"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2013-1179"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12360"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13143615"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurol.2023.03.003"},{"key":"e_1_2_8_35_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24065643"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2013.05.036"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2010.02.025"},{"key":"e_1_2_8_38_1","volume-title":"Corticosteroid Induced Myopathy","author":"Surmachevska N","year":"2023"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2016.02.1241"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1097\/RHU.0000000000001980"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1677\/JOE-07-0606"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.steroids.2023.109240"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11206202"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1080\/13685538.2021.1962840"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/pcan.2016.69"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12133"},{"key":"e_1_2_8_47_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.38.8850"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0263918"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-86079-4"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0000000000000697"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1177\/1759720X211015006"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-021-00873-w"},{"key":"e_1_2_8_53_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-020-04929-4"},{"key":"e_1_2_8_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-022-06454-y"},{"key":"e_1_2_8_55_1","doi-asserted-by":"publisher","DOI":"10.1592\/phco.24.17.1784.52334"},{"key":"e_1_2_8_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-4827(03)00034-X"},{"key":"e_1_2_8_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2023.115147"},{"key":"e_1_2_8_58_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.13000"},{"key":"e_1_2_8_59_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199004193221602"},{"key":"e_1_2_8_60_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.13212"},{"key":"e_1_2_8_61_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11657-023-01238-6"},{"key":"e_1_2_8_62_1","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2017.32.11.1857"},{"key":"e_1_2_8_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.13190"},{"key":"e_1_2_8_64_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12877-023-04012-y"},{"key":"e_1_2_8_65_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40520-022-02224-7"},{"key":"e_1_2_8_66_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep46369"},{"key":"e_1_2_8_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jjcc.2020.01.003"},{"key":"e_1_2_8_68_1","doi-asserted-by":"publisher","DOI":"10.1111\/hepr.13244"},{"key":"e_1_2_8_69_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0192990"},{"key":"e_1_2_8_70_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.50663"},{"key":"e_1_2_8_71_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glac139"},{"key":"e_1_2_8_72_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0002865"},{"key":"e_1_2_8_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2008.02.007"},{"key":"e_1_2_8_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2013.08.011"},{"key":"e_1_2_8_75_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells8121525"},{"key":"e_1_2_8_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtemb.2016.01.011"},{"key":"e_1_2_8_77_1","doi-asserted-by":"publisher","DOI":"10.15252\/embr.202153746"},{"key":"e_1_2_8_78_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.13277"},{"key":"e_1_2_8_79_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnut.2022.941093"},{"key":"e_1_2_8_80_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11030595"},{"key":"e_1_2_8_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2016.02.011"},{"key":"e_1_2_8_82_1","article-title":"What role do inflammatory cytokines play in cancer cachexia?","volume":"14","author":"Malla J","year":"2022","journal-title":"Cureus"},{"key":"e_1_2_8_83_1","doi-asserted-by":"publisher","DOI":"10.1111\/bpa.12955"},{"key":"e_1_2_8_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2020.07.004"},{"key":"e_1_2_8_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.accpm.2023.101202"},{"key":"e_1_2_8_86_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000031405"}],"container-title":["Geriatrics &amp; Gerontology International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ggi.14770","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,19]],"date-time":"2024-02-19T22:07:10Z","timestamp":1708380430000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ggi.14770"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12,29]]},"references-count":85,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["10.1111\/ggi.14770"],"URL":"https:\/\/doi.org\/10.1111\/ggi.14770","archive":["Portico"],"relation":{},"ISSN":["1444-1586","1447-0594"],"issn-type":[{"value":"1444-1586","type":"print"},{"value":"1447-0594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,12,29]]},"assertion":[{"value":"2023-11-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-29","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}