{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T22:16:17Z","timestamp":1783721777572,"version":"3.55.0"},"reference-count":35,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T00:00:00Z","timestamp":1728259200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["20720220061"],"award-info":[{"award-number":["20720220061"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Geriatrics Gerontology Int"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Previous studies have shown that chronic diseases are strongly linked to the development of sarcopenia. Few studies have assessed the relationship between multimorbidity patterns and sarcopenia. This study aimed to investigate the impact of multimorbidity patterns on sarcopenia transitions in Chinese older adults.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 3842 older adults (aged 66.7\u2009\u00b1\u20096.2\u2009years) with complete data at baseline and at least one follow\u2010up record (2\u2009years) were included from the China Health and Retirement Longitudinal Study. Multimorbidity patterns were identified using latent class analysis. Sarcopenia was determined by the Asian Working Group for Sarcopenia 2019 criteria. Multistage Markov modeling was used to explore the association of multimorbidity patterns with sarcopenia transitions after controlling for covariates in demographic features, health status and health\u2010related behaviours.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Four multimorbidity patterns were identified at baseline: respiratory (17.73%), osteoarthritis\u2010hypertension (22.23%), digestive\u2010osteoarthritis (26.78) and cardiometabolic (33.27%). Participants with non\u2010sarcopenia had 1\u2010year transition probability of developing possible sarcopenia (10.1%) or sarcopenia (5.4%). Compared with the group without chronic diseases, the presence of cardiometabolic pattern increased the risk of progression from non\u2010sarcopenia to possible sarcopenia (HR 1.43, 95% CI 1.05\u20132.95). The presence of the osteoarthritis\u2010hypertension pattern (HR 1.55, 95% CI 1.00\u20132.41) and the digestive\u2010osteoarthritis pattern (HR 1.78, 95% CI 1.20\u20132.66) were associated with the transition toward sarcopenia from non\u2010sarcopenia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Sarcopenia is a dynamic condition in older adults. To address sarcopenia in older adults, tailored interventions should be targeted at populations with different multimorbidity patterns. <jats:bold>Geriatr Gerontol Int 2024; 24: 1137\u20131143<\/jats:bold>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ggi.14984","type":"journal-article","created":{"date-parts":[[2024,10,8]],"date-time":"2024-10-08T06:33:53Z","timestamp":1728369233000},"page":"1137-1143","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Associations between multimorbidity patterns and sarcopenia transitions in Chinese older adults"],"prefix":"10.1111","volume":"24","author":[{"given":"Lingxiao","family":"He","sequence":"first","affiliation":[{"name":"Center for Aging and Health Research, School of Public Health Xiamen University  Xiamen China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shujing","family":"Lin","sequence":"additional","affiliation":[{"name":"Center for Aging and Health 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