{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T05:46:32Z","timestamp":1788846392390,"version":"build-2803163510"},"reference-count":28,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2024,11,12]],"date-time":"2024-11-12T00:00:00Z","timestamp":1731369600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["15dk0107003h0003"],"award-info":[{"award-number":["15dk0107003h0003"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["15dk0207004h0203"],"award-info":[{"award-number":["15dk0207004h0203"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["15dk0207019h0001"],"award-info":[{"award-number":["15dk0207019h0001"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["18dk0110021h0003"],"award-info":[{"award-number":["18dk0110021h0003"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009619","name":"Japan Agency for Medical Research and Development","doi-asserted-by":"publisher","award":["18le0110004h0002"],"award-info":[{"award-number":["18le0110004h0002"]}],"id":[{"id":"10.13039\/100009619","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007312","name":"National Center for Geriatrics and Gerontology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007312","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Geriatrics Gerontology Int"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Sarcopenia's high prevalence in older adults with cardiovascular disease (CVD) suggests that the risk of comorbidity in sarcopenia might also be increased during the at\u2010risk phase of CVD. However, the relationship between CVD risk and sarcopenia has not been elucidated. Therefore, the purpose of this cross\u2010sectional study was to investigate the association between CVD risk and sarcopenia in community\u2010dwelling Japanese older adults.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The participants in this cross\u2010sectional study included 14\u2009923 community\u2010dwelling Japanese older adults (mean age 73.2\u2009\u00b1\u20095.6\u2009years). The present study estimated the CVD risk using the revised World Health Organization risk chart, and classified CVD risk into \u201clow\u201d (&lt;10%) and \u201cmid\u2010high\u201d (\u226510%). Assessments of sarcopenia, muscle mass, muscle strength and gait speed were measured based on the clinical definitions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among the participants, 654 people (4.4%) had sarcopenia, and 4857 (32.6%) had CVD mid\u2010high risk. A multiple logistic model showed that the CVD mid\u2010high risk was associated with sarcopenia (odds ratio [OR] 1.55, 95% confidence interval [CI] 1.28\u20131.89). In addition, CVD mid\u2010high risk was associated with low muscle mass (OR 1.74, 95% CI 1.50\u20132.01), low muscle strength (OR 1.25, 95% CI 1.14\u20131.37) and slow gait speed (OR 1.17, 95% CI 1.07\u20131.27) in the adjusted model.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Among community\u2010dwelling older adults, high or moderate CVD risk was associated with an increased risk of sarcopenia. Our findings could help identify older adults with a future high risk for sarcopenia. <jats:bold>Geriatr Gerontol Int 2024; 24: 1328\u20131334<\/jats:bold>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ggi.15018","type":"journal-article","created":{"date-parts":[[2024,11,13]],"date-time":"2024-11-13T00:49:13Z","timestamp":1731458953000},"page":"1328-1334","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Association between cardiovascular disease risk and sarcopenia in community\u2010dwelling Japanese older adults"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6063-795X","authenticated-orcid":false,"given":"Kazuhei","family":"Nishimoto","sequence":"first","affiliation":[{"name":"Department of Preventive Gerontology Center for Gerontology and Social Science, Research Institute, National Center for Geriatrics and Gerontology  Obu Japan"},{"name":"Department of Physical Therapy Faculty of Health Sciences, Kyoto Tachibana University  Kyoto Japan"},{"name":"Medical Science Division, Department of Medical Sciences Graduate School of Medicine, Science and Technology, Shinshu University  Matsumoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0217-4728","authenticated-orcid":false,"given":"Kota","family":"Tsutsumimoto","sequence":"additional","affiliation":[{"name":"Department of Preventive Gerontology Center for Gerontology and Social Science, Research Institute, National Center for Geriatrics and Gerontology  Obu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1046-2976","authenticated-orcid":false,"given":"Sho","family":"Nakakubo","sequence":"additional","affiliation":[{"name":"Department of Preventive Gerontology Center for Gerontology and Social Science, Research Institute, National Center for Geriatrics and Gerontology  Obu 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National Center for Geriatrics and Gerontology  Obu Japan"},{"name":"Graduate School of Medicine, School of Health Sciences, Nagoya University  Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8111-6440","authenticated-orcid":false,"given":"Hiroyuki","family":"Shimada","sequence":"additional","affiliation":[{"name":"Department of Preventive Gerontology Center for Gerontology and Social Science, Research Institute, National Center for Geriatrics and Gerontology  Obu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,12]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afy169"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0169548"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2020.10.036"},{"key":"e_1_2_9_5_1","first-page":"1","article-title":"Sarcopenia is 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