{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T22:07:54Z","timestamp":1785881274258,"version":"3.56.0"},"reference-count":45,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,1,29]],"date-time":"2025-01-29T00:00:00Z","timestamp":1738108800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Geriatrics Gerontology Int"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Hearing loss is a public health issue; further studies are warranted to elucidate preventable factors. This study aimed to explore the associations of bilateral high\u2010frequency hearing loss (HFHL) with examination data and lifestyle behaviors, using the Comprehensive Health Checkup System (<jats:italic>Ningen Dock<\/jats:italic>) data in Japan.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This cross\u2010sectional study used <jats:italic>Ningen Dock<\/jats:italic> data obtained from the Seirei Health Care Division for 2020. HFHL was defined as inaudibility of 40\u2009dB at 4\u2009kHz. The Areal Deprivation Index (ADI) in Japan was used as an indicator of socioeconomic status. Binomial logistic regression analysis by sex was performed to evaluate the association of bilateral HFHL with each binarized examination data and lifestyle behavior, with age and the ADI as covariates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>This study included 36,137 participants (60% male; mean age, approximately 60\u2009years in both sexes). The odds ratios (ORs) for high uric acid (UA) levels in the examination data and current regular smoking in lifestyle behaviors were statistically significantly the highest (males: 1.27, 1.57; females: 3.56, 2.41, respectively). The OR for excessive alcohol consumption, especially large amounts consumed per occasion, was also statistically significant (males: 1.25; females: 2.15). Additionally, the ORs for high aminotransferase and \u03b3\u2010glutamyl transpeptidase levels in females were statistically significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>High UA levels, current regular smoking, and excessive alcohol consumption were associated with bilateral HFHL in both sexes. Especially, the findings regarding high UA levels and the large amount of alcohol consumption per occasion are novel, warranting longitudinal studies. <jats:bold>Geriatr Gerontol Int 2025; 25: 366\u2013373<\/jats:bold>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ggi.15062","type":"journal-article","created":{"date-parts":[[2025,1,30]],"date-time":"2025-01-30T02:48:32Z","timestamp":1738205312000},"page":"366-373","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Association of high\u2010frequency hearing loss with examination data and lifestyle in 36\u2009000 middle\u2010aged and older adults"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4391-346X","authenticated-orcid":false,"given":"Yuri","family":"Akamatsu","sequence":"first","affiliation":[{"name":"Department of Community Health and Preventive Medicine Hamamatsu University School of Medicine  Hamamatsu Japan"},{"name":"Department of Health Informatics School of Public Health, Kyoto University  Kyoto Japan"},{"name":"Seirei Center for Health Promotion and Prevention Medicine, Seirei Social Welfare Community  Hamamatsu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshiyuki","family":"Ojima","sequence":"additional","affiliation":[{"name":"Department of Community Health and Preventive Medicine Hamamatsu University School of Medicine  Hamamatsu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Nakanishi","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\/Head and Neck Surgery Hamamatsu University School of Medicine  Hamamatsu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiyoshi","family":"Misawa","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\/Head and Neck Surgery Hamamatsu University School of Medicine  Hamamatsu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeo","family":"Nakayama","sequence":"additional","affiliation":[{"name":"Department of Health Informatics School of Public Health, Kyoto University  Kyoto Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,29]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S195824"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2017.17040423"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)31363-6"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glu094"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archger.2010.04.023"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2010.02746.x"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.12864"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00516-X"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurpub\/ckr176"},{"key":"e_1_2_12_11_1","unstructured":"United Nations.World population prospects. 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