{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,8]],"date-time":"2026-08-08T07:42:16Z","timestamp":1786174936103,"version":"build-2736575974"},"reference-count":25,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T00:00:00Z","timestamp":1763424000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T00:00:00Z","timestamp":1763424000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100030953","name":"Tokyo Metropolitan Institute for Geriatrics and Gerontology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100030953","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Geriatrics Gerontology Int"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Geriatric experts have long debated the inclusion of appendicular lean soft tissue mass (ALSTM) in the diagnostic criteria for sarcopenia. This study examined whether a diagnostic model for sarcopenia that excludes appendicular lean soft tissue mass (ALSTM) is equivalent to one that includes ALSTM in discriminating health\u2010related outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Community\u2010dwelling older adults from the Itabashi Longitudinal Study on Aging in Tokyo, Japan, were included. Based on the AWGS2019 criteria, we developed two diagnostic models: Model 1, including low handgrip strength\/gait speed and low ALSTM assessed by bioelectrical impedance analysis, and Model 2, excluding low ALSTM. Health\u2010related outcomes were self\u2010reported falls and hospitalization in the past year. Differences in area under the receiver operating characteristic curve (AUC) and 95% confidence intervals (CI) between the two models were estimated using 1000 bootstrap samples.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In total, 2432 participants (median age: 76\u2009years; 53.2% men) without missing data were analyzed. Falls and hospitalization were reported by 17.8% and 15.3% of participants, respectively. The AUCs [95% CIs] of Models 1 and 2 were 0.61 [0.59, 0.64] and 0.61 [0.58, 0.64] for falls and 0.65 [0.62, 0.68] and 0.64 [0.61, 0.67] for hospitalization, respectively. The differences (Model 2\u2014Model 1) in AUCs [95% CI] between the two models were \u22120.004 [\u22120.015, 0.006] for falls and \u22120.004 [\u22120.014, 0.004] for hospitalization, with the CIs within the pre\u2010specified equivalence margin (\u00b10.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Diagnostic models excluding ALSTM demonstrated equivalent discrimination ability to those including ALSTM, raising questions about the necessity of ALSTM assessment for sarcopenia diagnosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ggi.70252","type":"journal-article","created":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T09:52:58Z","timestamp":1763459578000},"page":"1840-1845","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Is Appendicular Lean Soft Tissue Mass a Clinically Valid Diagnostic Marker for Sarcopenia?"],"prefix":"10.1111","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5744-1961","authenticated-orcid":false,"given":"Yosuke","family":"Osuka","sequence":"first","affiliation":[{"name":"Department of Frailty Research Center for Gerontology and Social Science, Research Institute, National Center for Geriatrics and Gerontology  Obu Aichi Japan"},{"name":"Research Team for Promoting Independence and Mental Health, Tokyo Metropolitan Institute for Geriatrics and Gerontology  Itabashi Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-8728-5071","authenticated-orcid":false,"given":"Sho","family":"Hatanaka","sequence":"additional","affiliation":[{"name":"Research Team for Promoting Independence and Mental Health, Tokyo Metropolitan Institute for Geriatrics and Gerontology  Itabashi Tokyo 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