{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T13:19:27Z","timestamp":1790342367247,"version":"4.1.0"},"reference-count":31,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2018\/22186\u20102"],"award-info":[{"award-number":["2018\/22186\u20102"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2022\/14142\u20100"],"award-info":[{"award-number":["2022\/14142\u20100"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["88887.484551\/2020\u201000"],"award-info":[{"award-number":["88887.484551\/2020\u201000"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Geriatrics Gerontology Int"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Social frailty is linked to adverse health outcomes, including depression, especially in older and chronically ill individuals. This study aimed to assess the prevalence and associated factors of social frailty in Brazilian CKD patients undergoing hemodialysis or kidney transplantation and to examine its predictive role in the development of depressive symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This cross\u2010sectional, correlational, and comparative study included 284 patients with CKD from S\u00e3o Paulo, Brazil. Data were collected using validated instruments: HALFT Social Frailty Scale, Patient Health Questionnaire\u20109 (PHQ\u20109), and Medical Outcomes Study Social Support Scale (MOS). Two multiple linear regression (MLR) models were used to assess predictors of social frailty and depressive symptoms, adjusting for sociodemographic and clinical variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Social frailty was significantly more prevalent among HD patients (51.2%) compared to TX patients (24%). Social support was negatively associated with social frailty (\u03b2\u2009=\u2009\u22120.40;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Other predictors of greater social frailty included lower income (\u03b2\u2009=\u20090.51 for \u2264\u20091 minimum wage), number of medications (\u03b2\u2009=\u20090.11), and lower education (\u03b2\u2009=\u2009\u22120.13). In turn, social frailty was the strongest predictor of depressive symptoms (\u03b2\u2009=\u20090.60;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). TX status and male sex were associated with lower depression scores.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Social frailty is highly prevalent in CKD patients, particularly those undergoing HD, and strongly predicts depressive symptoms. Strategies to enhance social support and reduce socioeconomic vulnerability may help mitigate mental health burdens in this population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ggi.70317","type":"journal-article","created":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T05:09:18Z","timestamp":1767330558000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Predictors of Social Frailty and Depression in Brazilian Patients With Chronic Kidney Disease: A Cross\u2010Sectional Study"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1572-5322","authenticated-orcid":false,"given":"Diana Gabriela Mendes","family":"dos Santos","sequence":"first","affiliation":[{"name":"Department of Nursing Federal University of S\u00e3o Carlos S\u00e3o Carlos Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luma","family":"Geraigire","sequence":"additional","affiliation":[{"name":"Department of Gerontology Federal University of S\u00e3o Carlos S\u00e3o Carlos Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Layana Giselly Silva","family":"Ferreira","sequence":"additional","affiliation":[{"name":"Department of Nursing Federal University of S\u00e3o Carlos S\u00e3o Carlos Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cleanderson","family":"Costa da Silva","sequence":"additional","affiliation":[{"name":"Department of Gerontology Federal University of S\u00e3o Carlos S\u00e3o Carlos Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Carolina","family":"de Souza Dinardi","sequence":"additional","affiliation":[{"name":"Department of Gerontology Federal University of S\u00e3o Carlos S\u00e3o Carlos Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marisa Silvana","family":"Zazzetta","sequence":"additional","affiliation":[{"name":"Department of Gerontology Federal University of S\u00e3o Carlos S\u00e3o Carlos Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabiana","family":"de Souza Orlandi","sequence":"additional","affiliation":[{"name":"Department of Gerontology Federal University of S\u00e3o Carlos S\u00e3o Carlos Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,1,1]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2009.11.008"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10433\u2010017\u20100414\u20107"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ggi.14223"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jnha.2025.100496"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamda.2022.10.007"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40520\u2010023\u201002421\u2010y"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.17058"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598\u2010024\u201053984\u20103"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12889\u2010025\u201021662\u20102"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph192416683"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.5489\/cuaj.8236"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2023.09.033"},{"key":"e_1_2_11_14_1","unstructured":"Brazil. Ministry of Health. Secretariat of Health Surveillance and Environment \u201cEpidemiological Bulletin\u2014Volume 55 No. 12: Overview of Chronic Kidney Disease in Brazil From 2010 To 2023 [Internet]. Bras\u00edlia: Ministry of Health; 2024\u201d."},{"key":"e_1_2_11_15_1","unstructured":"Brazilian Institute of Geography and Statistics\u2014IBGE \u201cNational Health Survey 2019: Perception of Health Status Lifestyle Chronic Diseases and Oral Health [Internet]. Rio de Janeiro IBGE; 2020\u201d."},{"key":"e_1_2_11_16_1","unstructured":"Brazilian Association of Organ Transplantation\u2014ABTO \u201cBrazilian Transplant Registry\u2014Updated Population [Internet]. S\u00e3o Paulo ABTO; 2024\u201d."},{"key":"e_1_2_11_17_1","doi-asserted-by":"publisher","DOI":"10.1590\/2175\u20108239\u2010JBN\u20102018\u20100224"},{"key":"e_1_2_11_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913\u2010024\u201011258\u20108"},{"key":"e_1_2_11_19_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2017.05.019"},{"key":"e_1_2_11_20_1","volume-title":"Designing Clinical Research","author":"Hulley S. B.","year":"2007"},{"key":"e_1_2_11_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12603\u2010018\u20101054\u20100"},{"key":"e_1_2_11_22_1","doi-asserted-by":"publisher","DOI":"10.1590\/1516\u20103180.2022.0020.07042022"},{"key":"e_1_2_11_23_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525\u20101497.2001.016009606.x"},{"key":"e_1_2_11_24_1","doi-asserted-by":"publisher","DOI":"10.1590\/0102\u2010311x00144612"},{"key":"e_1_2_11_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/0277\u20109536(91)90150\u2010b"},{"key":"e_1_2_11_26_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0102\u2010311X2005000200004"},{"key":"e_1_2_11_27_1","volume-title":"An R Companion to Applied Regression","author":"Fox J.","year":"2018"},{"key":"e_1_2_11_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12888\u2010023\u201005249\u2010y"},{"key":"e_1_2_11_29_1","doi-asserted-by":"publisher","DOI":"10.1097\/MNH.0000000000000741"},{"key":"e_1_2_11_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2022.09.030"},{"key":"e_1_2_11_31_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471\u20102369\u201014\u201078"},{"key":"e_1_2_11_32_1","doi-asserted-by":"publisher","DOI":"10.4103\/jesnt.jesnt_1_24"}],"container-title":["Geriatrics &amp; Gerontology International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ggi.70317","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ggi.70317","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ggi.70317","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T05:07:15Z","timestamp":1782709635000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/ggi.70317"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1111\/ggi.70317"],"URL":"https:\/\/doi.org\/10.1111\/ggi.70317","archive":["Portico"],"relation":{},"ISSN":["1444-1586","1447-0594"],"issn-type":[{"value":"1444-1586","type":"print"},{"value":"1447-0594","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-02-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70317"}}