{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T05:45:17Z","timestamp":1782711917245,"version":"3.54.5"},"reference-count":28,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:00:00Z","timestamp":1768435200000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP20K07803"],"award-info":[{"award-number":["JP20K07803"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Geriatrics Gerontology Int"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Sarcopenia increases the risk of long\u2010term care, disease development, and mortality in older adults. It is also a risk factor for cardiovascular disease and vice versa. Using cross\u2010sectional and longitudinal cohort study designs, we investigated the association between the carotid intima\u2010media thickness (CIMT) and sarcopenia in older adults.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data were extracted from the Septuagenarians, Octogenarians, Nonagenarians Investigation with Centenarians (SONIC) study. Using data from Wave 3 of the SONIC participants, we examined the association between CIMT and sarcopenia using cross\u2010sectional analysis and the association between CIMT at baseline and sarcopenia status 3\u2009years later (Wave 4) in a longitudinal study. Sarcopenia was diagnosed according to the Asian Working Group for Sarcopenia (AWGS) 2019 guidelines.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The cross\u2010sectional study included 735 participants (347 males, mean age: 76.0\u2009\u00b1\u20090.9\u2009years); the longitudinal study included 498 participants (247 males, mean age: 75.9\u2009\u00b1\u20090.9\u2009years). In the cross\u2010sectional study, 130 (17.7%) participants had sarcopenia; multiple logistic regression analysis revealed an odds ratio (OR) of 1.55 (95% confidence interval [CI]: 1.15\u20132.07) for sarcopenia for every 1\u2009mm increase in the maximum CIMT. In the longitudinal study, 100 participants (20.1%) had sarcopenia at Wave 4. Multiple logistic regression analysis revealed an OR of 1.63 for sarcopenia (95% CI: 1.13\u20132.36) for each 1\u2009mm increase from the baseline maximum CIMT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>CIMT was associated with sarcopenia. These results help clarify the pathophysiology of sarcopenia and the possible use of the CIMT as a marker to identify individuals at high risk of sarcopenia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ggi.70326","type":"journal-article","created":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T06:25:10Z","timestamp":1768544710000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Longitudinal Association Between the Carotid Intima\u2010Media Thickness and Sarcopenia in an Older Japanese Population: The\n                    <scp>SONIC<\/scp>\n                    Study"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-8574-1494","authenticated-orcid":false,"given":"Ken","family":"Terashima","sequence":"first","affiliation":[{"name":"Department of Geriatric and General Medicine Osaka University Graduate School of Medicine  Suita Osaka 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