{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,7]],"date-time":"2026-09-07T13:15:49Z","timestamp":1788786949691,"version":"build-2803163510"},"reference-count":30,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:00:00Z","timestamp":1782950400000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Geriatrics Gerontology Int"],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To evaluate whether preoperative hemoglobin (Hb) decline independently predicts mortality in older hip fracture patients and whether commonly used Hb\u2010drop thresholds add prognostic value beyond established clinical risk factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed a retrospective cohort study of consecutive patients aged \u2265\u200965\u2009years undergoing surgery for acute hip fracture at a level I trauma center (2019\u20132024). Preoperative Hb drop was defined as the difference between emergency department admission Hb and pre\u2010anesthesia Hb. Six Hb\u2010drop thresholds (\u2265\u20091.0, \u2265\u20091.5, \u2265\u20092.0, \u2265\u20092.5, \u2265\u20093.0, \u2265\u20094.0\u2009g\/dL) were evaluated. The primary outcome was 30\u2010day all\u2010cause mortality; secondary outcomes included 7\u2010day, 90\u2010day, 6\u2010month, and 1\u2010year mortality. Multivariate logistic regression for each threshold adjusted for age \u2265\u200985\u2009years, ASA class \u2265\u20093, chronic kidney disease, and admission Hb &lt;\u200910\u2009g\/dL.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 1832 patients (mean age 82.6\u2009\u00b1\u20098.0\u2009years; 65.8% women), 30\u2010day mortality was 4.3% (78\/1832). A preoperative Hb drop \u2265\u20092\u2009g\/dL occurred in 49.3% of patients, with similar prevalence among survivors and non\u2010survivors (49.2% vs. 51.3%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.734). No Hb\u2010drop threshold was independently associated with 30\u2010day mortality (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05); for the \u2265\u20092\u2009g\/dL threshold, adjusted odds ratio (OR) was 1.08 (95% CI 0.66\u20131.77,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.757). In contrast, age \u2265\u200985\u2009years (adjusted OR 3.39, 95% CI 1.98\u20135.79,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and ASA \u2265\u20093 (adjusted OR 2.02, 95% CI 1.08\u20133.78,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.029) were independently associated with 30\u2010day mortality. No Hb\u2010drop threshold showed an independent association with mortality at any timepoint (7\u2010day, 90\u2010day, 6\u2010month, 1\u2010year).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In older hip fracture patients, preoperative Hb decline\u2014including the widely used \u2265\u20092\u2009g\/dL threshold\u2014was not an independent prognostic factor for mortality. Admission\u2010available clinical factors are more informative for short\u2010term mortality risk assessment than the preoperative Hb drop in this population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ggi.70630","type":"journal-article","created":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T14:59:58Z","timestamp":1783004398000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Preoperative Hemoglobin Decline Is Not an Independent Prognostic Factor for Mortality in Older Hip Fracture Patients"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2038-9538","authenticated-orcid":false,"given":"Nadav","family":"Graif","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery Tel Aviv Sourasky Medical Center  Tel Aviv Israel"},{"name":"Gray Faculty of Medical and Health Sciences Tel Aviv University, Ramat Aviv  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lera","family":"Sotnikov","sequence":"additional","affiliation":[{"name":"Gray Faculty of Medical and Health Sciences Tel Aviv University, Ramat Aviv  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaniv","family":"Warschawski","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Tel Aviv Sourasky Medical Center  Tel Aviv Israel"},{"name":"Gray Faculty of Medical and Health Sciences Tel Aviv University, Ramat Aviv  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5004-1623","authenticated-orcid":false,"given":"Nissan","family":"Amzallag","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Tel Aviv Sourasky Medical Center  Tel Aviv Israel"},{"name":"Gray Faculty of Medical and Health Sciences Tel Aviv University, Ramat Aviv  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lior","family":"Shabtai","sequence":"additional","affiliation":[{"name":"Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell 500 Hofstra University  Hempstead New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Morsi","family":"Khashan","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Tel Aviv Sourasky Medical Center  Tel Aviv Israel"},{"name":"Gray Faculty of Medical and Health Sciences Tel Aviv University, Ramat Aviv  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gil","family":"Rachevski","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Tel Aviv Sourasky Medical Center  Tel Aviv Israel"},{"name":"Gray Faculty of Medical and Health Sciences Tel Aviv University, Ramat Aviv  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Itay","family":"Ashkenazi","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery Tel Aviv Sourasky Medical Center  Tel Aviv Israel"},{"name":"Gray Faculty of Medical and Health Sciences Tel Aviv University, Ramat Aviv  Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,7,2]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.1462"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.5312\/wjo.v10.i3.166"},{"key":"e_1_2_11_4_1","article-title":"Hidden Blood Loss After Surgery for Hip Fracture","volume":"88","author":"Foss N. 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