{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T18:34:14Z","timestamp":1790274854542,"version":"4.1.0"},"reference-count":77,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T00:00:00Z","timestamp":1787616000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100005122","name":"Japanese Physical Therapy Association","doi-asserted-by":"publisher","award":["YB010"],"award-info":[{"award-number":["YB010"]}],"id":[{"id":"10.13039\/501100005122","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Geriatrics Gerontology Int"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To determine whether frailty is associated with activities of daily living (ADL) and other clinical outcomes in hospitalized older adults.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>MEDLINE, Embase and CENTRAL were searched for English\u2010language cohort studies published from 1 January 2001 to 23 October 2025. Eligible studies included hospitalized adults aged \u2265\u200965\u2009years (or samples with \u2265\u200980% aged \u2265\u200965\u2009years), used a defined frailty measure and compared frail with non\u2010frail participants. Two reviewers independently selected studies, extracted data and assessed risk of bias using the Quality In Prognosis Studies tool. Random\u2010effects meta\u2010analyses generated standardized mean differences (SMDs) or risk ratios (RRs) with 95% confidence intervals (CIs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Fifty\u2010seven cohort studies were included. Frailty was associated with worse ADL status (SMD \u22121.04, 95% CI \u22121.89 to \u22120.20), higher mortality (RR 2.26, 95% CI 1.86\u20132.76), lower likelihood of discharge home (RR 0.79, 95% CI 0.73\u20130.86), and higher 30\u2010day (RR 1.47, 95% CI 1.13\u20131.90) and 90\u2010day readmission risks (RR 1.75, 95% CI 1.07\u20132.86). Pneumonia risk was not statistically significant. Heterogeneity was substantial to considerable for all pooled outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Frailty identifies hospitalized older adults at increased risk of functional dependence, mortality, non\u2010home discharge, and readmission. Substantial heterogeneity and residual confounding warrant cautious interpretation and support standardized frailty and functional\u2010outcome assessment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ggi.70811","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T03:47:36Z","timestamp":1787716056000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of Frailty on Activities of Daily Living in Hospitalized Older Adults: A Systematic Review and Meta\u2010Analysis"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0490-8393","authenticated-orcid":false,"given":"Tomohiko","family":"Kamo","sequence":"first","affiliation":[{"name":"Department of Physical Therapy, Faculty of Rehabilitation Gunma Paz University  Takasaki 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