{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T07:01:59Z","timestamp":1790233319934,"version":"4.1.0"},"reference-count":30,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T00:00:00Z","timestamp":1789948800000},"content-version":"vor","delay-in-days":20,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Geriatrics Gerontology Int"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To determine the prevalence of osteosarcopenia in older patients with rheumatoid arthritis (RA) compared with age\u2010 and sex\u2010matched controls and to examine its relationship with RA\u2010related clinical, nutritional, and functional parameters, including rheumatoid cachexia (RC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective cross\u2010sectional study included 268 individuals: 134 patients aged \u2265\u200960\u2009years with RA and 134 age\u2010 and sex\u2010matched controls. Fat mass index (FMI), fat\u2010free mass index (FFMI), and muscle mass were assessed by bioelectrical impedance analysis. Sarcopenia was defined using an EWGSOP2\u2010aligned approach and osteoporosis according to WHO criteria. RC was defined as FFMI &lt;\u200910th percentile and FMI &gt;\u200925th percentile. Disability and nutritional risk were assessed using the Lawton\u2013Brody IADL and MNA\u2010SF.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Compared with controls, patients with RA had lower BMI, FFMI, and FMI (all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009\u2264\u20090.001), while visceral fat did not differ. Sarcopenia, osteoporosis, and osteosarcopenia were more prevalent in RA than in controls (49.3% vs. 20.9%, 53.0% vs. 32.1%, and 28.4% vs. 10.4%; all\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Within RA, osteosarcopenia was associated with lower serum albumin and IADL scores and higher RC prevalence (39.5%). RC remained independently associated with osteosarcopenia after adjustment for demographic, comorbidity, and RA\u2010specific factors (adjusted OR 10.43, 95% CI 3.13\u201334.79;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Osteosarcopenia was more than twice as common in older patients with RA than in matched controls. Rheumatoid cachexia clustered within the osteosarcopenia subgroup and remained independently associated with osteosarcopenia. These findings support osteosarcopenia as a distinct catabolic phenotype in RA characterized by rheumatoid cachexia, lower serum albumin levels, and greater functional impairment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ggi.70847","type":"journal-article","created":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T00:05:12Z","timestamp":1790035512000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Osteosarcopenia in Older Adults With Rheumatoid Arthritis: Clinical Correlates and Its Association With Rheumatoid Cachexia"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7470-7488","authenticated-orcid":false,"given":"Firuzan F\u0131rat","family":"Ozer","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Division of Geriatrics Erciyes University  Kayseri T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saliha","family":"Sunkak","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Kayseri City Hospital  Kayseri T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuhal","family":"Bilgili","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Geriatrics Erciyes University  Kayseri T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8914-7022","authenticated-orcid":false,"given":"\u00d6zlem","family":"\u015een","sequence":"additional","affiliation":[{"name":"Department of Rheumatology Kayseri City Hospital  Kayseri T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emine","family":"G\u00fcven","sequence":"additional","affiliation":[{"name":"Department of Gerontology Kayseri City Hospital  Kayseri T\u00fcrkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,21]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keaa755"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu13020291"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.5114\/reum.2020.95364"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12877\u2010023\u201004085\u20109"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.afos.2021.11.002"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu17132186"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/03009740802055984"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcsm.12320"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2010.138461"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00198\u2010014\u20102794\u20102"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afy169"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.2000.89.2.465"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwh058"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2021.11.014"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532\u20105415.2005.53172.x"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(94)90129-5"},{"issue":"5","key":"e_1_2_10_18_1","first-page":"S40","article-title":"The Disease Activity Score (DAS) and the Disease Activity Score Using 28 Joint Counts (DAS28) in the Management of Rheumatoid Arthritis","volume":"34","author":"Riel P. 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