{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T09:42:51Z","timestamp":1792489371328,"version":"4.5.0"},"reference-count":27,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:00:00Z","timestamp":1792454400000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Geriatrics Gerontology Int"],"published-print":{"date-parts":[[2026,10]]},"abstract":"ABSTRACT<\/jats:title>\n \n Aim<\/jats:title>\n To evaluate whether nocturia\u2009\u2265\u20093\/night stratifies 5\u2010year fragility\u2010fracture risk in older urology outpatients and to explore its prognostic performance alongside the N\u2010QoL and IPSS.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n We conducted a retrospective cohort study of urology outpatients aged \u2265\u200965\u2009years at Hachinohe City Hospital, Japan, between 2015 and 2024. After exclusion of patients with prior fragility fracture, bone metastasis, or pathological fracture, and application of a 3\u2010month landmark, 2290 participants were included. The primary outcome was first non\u2010pathological fragility fracture. Bone metastasis and death were treated as competing events. Fine\u2013Gray subdistribution hazard models were adjusted for age, sex, hypertension, and diabetes. To complement effect estimates, standardized 5\u2010year cumulative incidence was estimated using model\u2010based standardization.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Over a median follow\u2010up of 48.1\u2009months, 98 fragility fractures occurred; 42 bone metastases and 18 deaths were treated as competing events. Nocturia\u2009\u2265\u20093\/night was associated with higher fracture risk than nocturia\u2009<\u20093\/night (subdistribution hazard ratio [sHR] 2.11, 95% confidence interval [CI] 1.41\u20133.17). Impaired N\u2010QoL was also associated with higher risk (sHR 1.92, 95% CI 1.12\u20133.30), whereas severe IPSS showed a weaker association (sHR 1.79, 95% CI 1.00\u20133.22). The standardized 5\u2010year fracture risk was 9.8% for nocturia\u2009\u2265\u20093\/night and 4.8% for nocturia\u2009<\u20093\/night, corresponding to an absolute difference of 5.0 percentage points.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Nocturia\u2009\u2265\u20093\/night was associated with higher 5\u2010year fragility\u2010fracture risk and may prompt consideration of falls and bone\u2010health assessment in older urology outpatients.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ggi.70886","type":"journal-article","created":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T09:21:45Z","timestamp":1792488105000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Nocturia\u2009\u2265\u20093\/Night and 5\u2010Year Fragility Fracture Risk in Older Urology Outpatients"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4238-866X","authenticated-orcid":false,"given":"Kunihisa","family":"Nezu","sequence":"first","affiliation":[{"name":"Department of Urology Hachinohe City Hospital Aomori Japan"},{"name":"Department of Urology Tohoku University Graduate School of Medicine Sendai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maiko","family":"Yamashita","sequence":"additional","affiliation":[{"name":"Department of Urology Hachinohe City Hospital Aomori Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shingo","family":"Myoen","sequence":"additional","affiliation":[{"name":"Department of Urology Hachinohe City Hospital Aomori Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoki","family":"Kawamorita","sequence":"additional","affiliation":[{"name":"Department of Urology Tohoku University Graduate School of Medicine Sendai Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,20]]},"reference":[{"issue":"1","key":"e_1_2_12_2_1","doi-asserted-by":"crossref","first-page":"36","DOI":"10.5534\/wjmh.240237","article-title":"Nocturia, Sleep Quality, and Mortality: A Systematic Review and Meta\u2010Analysis","volume":"44","author":"Lavadia A. 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