{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T17:53:38Z","timestamp":1793210018191,"version":"4.5.0"},"reference-count":43,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,9,24]],"date-time":"2013-09-24T00:00:00Z","timestamp":1379980800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>Haematomas and recurrent haemarthroses are a common problem in haemophilia patients from early age. Early diagnosis is critical in preventing haemophilic arthritis, and recent years have seen excellent advances in musculoskeletal ultrasound as a diagnostic tool in soft tissue lesions. In this study, we compared the results of ultrasound imaging for the diagnosis of musculoskeletal injuries in haemophilia patients with scores obtained using magnetic resonance (<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>) scans. A total of 61 haemophilia patients aged 4\u201382\u00a0years were included in this study. Both knees and ankles of each patient were assessed using the Gilbert (clinical assessment) and Pettersson scores (X\u2010ray assessment). Patients with severe haemophilia (<jats:italic>n<\/jats:italic>\u00a0=\u00a030) were examined using ultrasound and <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> (Denver scoring system). Results obtained with ultrasound and <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> in severe patients were correlated using the Pearson test. In patients with severe haemophilia, normal joints were similarly assessed with <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> and ultrasound (<jats:italic>\u03ba<\/jats:italic>\u00a0=\u00a01.000). By component of joint assessment, haemarthrosis was similarly diagnosed with both techniques in all joints (<jats:italic>\u03ba<\/jats:italic>\u00a0=\u00a01.000). A good positive correlation was found between these techniques in detecting and locating synovial hyperplasia (<jats:italic>\u03ba<\/jats:italic>\u00a0=\u00a00.839\u20131.000, knees and ankles respectively), and erosion of margins (<jats:italic>\u03ba<\/jats:italic>\u00a0=\u00a00.850\u20131.000). The presence of bone cysts or cartilage loss was better detected with <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> (<jats:italic>\u03ba<\/jats:italic>\u00a0=\u00a00.643\u20130.552 for knees and ankles, and <jats:italic>\u03ba<\/jats:italic>\u00a0=\u00a00.643\u20130.462 respectively). Ultrasound is useful in detecting joint bleeds, synovial hyperplasia and joint erosions, with results comparable to those of <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>. A quick and affordable technique, ultrasound imaging may be useful for monitoring joint bleeds and structure normalization and maintenance in routine practice.<\/jats:p>","DOI":"10.1111\/hae.12268","type":"journal-article","created":{"date-parts":[[2013,10,11]],"date-time":"2013-10-11T22:11:57Z","timestamp":1381529517000},"source":"Crossref","is-referenced-by-count":55,"title":["Comparison of ultrasound and magnetic resonance imaging for diagnosis and follow\u2010up of joint lesions in patients with haemophilia"],"prefix":"10.1111","volume":"20","author":[{"given":"C.","family":"Sierra Aisa","sequence":"first","affiliation":[{"name":"Hospital Universitario de Cruces San Vicente de Barakaldo Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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