{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T08:53:36Z","timestamp":1768294416866,"version":"3.49.0"},"reference-count":26,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,11,22]],"date-time":"2013-11-22T00:00:00Z","timestamp":1385078400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2014,5]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>An elevated body mass index (<jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content>) may make venipuncture more difficult, potentially impacting the use of home infusion (<jats:styled-content style=\"fixed-case\">HI<\/jats:styled-content>) and self\u2010infusion (<jats:styled-content style=\"fixed-case\">SI<\/jats:styled-content>). We sought to determine whether above\u2010normal <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> is associated with decreased use of <jats:styled-content style=\"fixed-case\">HI<\/jats:styled-content> treatment and <jats:styled-content style=\"fixed-case\">SI<\/jats:styled-content> of clotting factor concentrate among haemophilic persons. We analysed data from 10\u00a0814 male patients with haemophilia A and B (45% with severe disease) aged 6\u201379\u00a0years enrolled in the Centers for Disease Control and Prevention Universal Data Collection surveillance project between 1998 and 2008. Associations between the use of <jats:styled-content style=\"fixed-case\">HI<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">SI<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">BMI<\/jats:styled-content> were evaluated using logistic regression. Fifty per cent of haemophilic men were overweight or obese, similar to rates reported among the general <jats:styled-content style=\"fixed-case\">US<\/jats:styled-content> population by the 2007\u20132008 National Health and Nutrition Examination Survey [Flegal, KM <jats:italic>et\u00a0al<\/jats:italic>., JAMA 2010;<jats:bold>303<\/jats:bold>:235\u2013241;]. Twenty per cent of children and 22% of teens were obese, as were 28% of adults [Ogden, CL <jats:italic>et al<\/jats:italic>., JAMA 2010;303:235, 242]. Overall, 70% of the study sample used <jats:styled-content style=\"fixed-case\">HI<\/jats:styled-content>; 44% of those who used <jats:styled-content style=\"fixed-case\">HI<\/jats:styled-content> also used <jats:styled-content style=\"fixed-case\">SI<\/jats:styled-content>. Overweight and obese men were each less likely to use <jats:styled-content style=\"fixed-case\">HI<\/jats:styled-content> than those of normal weight [odds ratio (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>) 0.8; 95% confidence interval (<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>) 0.7\u20131.0 and <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 0.7; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.6\u20130.8 respectively]. Obese teens and adult men were also less likely to practice <jats:styled-content style=\"fixed-case\">SI<\/jats:styled-content> than teens and adults of normal weight (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 0.8; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 0.7\u20130.9 for each). We conclude that overweight and obese haemophilic men are less likely to use <jats:styled-content style=\"fixed-case\">HI<\/jats:styled-content> and obese men are less likely to use <jats:styled-content style=\"fixed-case\">SI<\/jats:styled-content> than their normal\u2010weight counterparts.<\/jats:p>","DOI":"10.1111\/hae.12303","type":"journal-article","created":{"date-parts":[[2013,11,23]],"date-time":"2013-11-23T06:51:12Z","timestamp":1385189472000},"page":"340-348","source":"Crossref","is-referenced-by-count":15,"title":["Association of overweight and obesity with the use of self and home\u2010based infusion therapy among haemophilic men"],"prefix":"10.1111","volume":"20","author":[{"given":"M.","family":"Ullman","sequence":"first","affiliation":[{"name":"Gulf States Hemophilia &amp; Thrombophilia Center University of Texas Health Science Center at Houston Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Q. C.","family":"Zhang","sequence":"additional","affiliation":[{"name":"Division of Blood Disorders National Center on Birth Defects and Developmental Disabilities CDC Atlanta GA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Brown","sequence":"additional","affiliation":[{"name":"Gulf States Hemophilia &amp; Thrombophilia Center University of Texas Health Science Center at Houston Houston TX USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Grant","sequence":"additional","affiliation":[{"name":"Division of Blood Disorders National Center on Birth Defects and Developmental Disabilities CDC Atlanta GA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. M.","family":"Soucie","sequence":"additional","affiliation":[{"name":"Division of Blood Disorders National Center on Birth Defects and Developmental Disabilities CDC Atlanta GA USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"on Behalf of the Hemophilia Treatment Center Network Investigators","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,11,22]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"World Federation of Hemophilia.Guidelines for the management of hemophilia. Available athttp:\/\/www.wfh.org. 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