{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T22:38:12Z","timestamp":1767825492719,"version":"3.49.0"},"reference-count":36,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2014,5,26]],"date-time":"2014-05-26T00:00:00Z","timestamp":1401062400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:title>Summary<\/jats:title><jats:p>To compare the use of 740\u00a0Mbq (20\u00a0mCi) of <jats:sup>153<\/jats:sup>Sm and 185 Mbq (5mCi) of <jats:sup>90<\/jats:sup>Y, both labelling hydroxyapatite (HA), for knee synovectomy in haemophilic patients, 1\u00a0year after the intervention. Thirty three men (36 knees) were studied, divided into two groups: 1 \u2013 treatment using 740 Mbq of <jats:sup>153<\/jats:sup>Sm\u2010HA: 20 knees of 18 patients, with mean age of 21.4\u00a0\u00b1\u00a013.3\u00a0years (ranging from 7 to 56\u00a0years) and mean Pettersson score of 5.3; 2 \u2013 treatment using 185 Mbq of <jats:sup>90<\/jats:sup>Y\u2010HA: 16 knees of 15 patients, with mean age of 26.3\u00a0\u00b1\u00a010.3 (ranging from 7 to 51\u00a0years) and mean Pettersson score of 6.3. The following criteria were adopted for the evaluation before and 1\u00a0year after synovectomy: reduction in haemarthrosis episodes and pain using a visual analogue scale, as well as improved joint mobility. The occurrence of adverse events in the treatment was also considered. The chi\u2010square, Wilcoxon and Mann\u2013Whitney tests were used with <jats:italic>P<\/jats:italic>\u00a0\u2264\u00a00.05 set as significant. The occurrence of haemarthrosis declined by 65.7% with the use of <jats:sup>153<\/jats:sup>Sm\u2010HA and 82.6% for <jats:sup>90<\/jats:sup>Y\u2010HA, with no statistical difference between the groups (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.632); pain reduction was 42.5% in group 1 and 30.7% in group 2, once again with no statistical difference (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.637). Improvement in joint mobility was not significant for both groups. Two cases of mild reactive synovitis were observed in group 1 and one in group 2, which cleared up without medical intervention. Although the beta energy from <jats:sup>90<\/jats:sup>Y is the gold standard for knee synovectomy, higher activities of <jats:sup>153<\/jats:sup>Sm may be used in places which have only production of this material.<\/jats:p>","DOI":"10.1111\/hae.12453","type":"journal-article","created":{"date-parts":[[2014,5,27]],"date-time":"2014-05-27T04:16:11Z","timestamp":1401164171000},"page":"873-878","source":"Crossref","is-referenced-by-count":6,"title":["Comparison of the effect of knee synovectomy in haemophilic patients with <sup>153<\/sup>Sm\u2010 and <sup>90<\/sup>Y \u2010labelled hydroxyapatite 1\u00a0year after"],"prefix":"10.1111","volume":"20","author":[{"given":"J.","family":"Calegaro","sequence":"first","affiliation":[{"name":"Hospital de Base Nuclear Medicine Service S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Silveira","sequence":"additional","affiliation":[{"name":"Hospital de Base Haematology Service S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Hage","sequence":"additional","affiliation":[{"name":"Hospital de Base. Orthopedic Service S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Sayago","sequence":"additional","affiliation":[{"name":"IHTC Bras\u00edlia Physiotherapy S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"de Landa","sequence":"additional","affiliation":[{"name":"Hospital de Base Nuclear Medicine Service S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Mengatti","sequence":"additional","affiliation":[{"name":"IPEN\u2010CNEN Radiopharmacy Center S\u00e3o Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. 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