{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T05:27:27Z","timestamp":1771046847893,"version":"3.50.1"},"reference-count":8,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,12,29]],"date-time":"2014-12-29T00:00:00Z","timestamp":1419811200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"China Postdoctoral Science Foundation on the 53th general program","award":["2013M531404"],"award-info":[{"award-number":["2013M531404"]}]},{"name":"the Specialized Research Fund for the Doctoral Program of Higher Education of China","award":["20123201120018"],"award-info":[{"award-number":["20123201120018"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2015,1]]},"abstract":"Summary<\/jats:title>To evaluate the efficacy of external fixators(EF<\/jats:styled-content>s) for management of open fractures of tibia and fibula in patients with haemophilia A. EF<\/jats:styled-content>s are commonly used in the clinical management of infec\u2010ted or open fractures when internal fixation is contraindicated and plaster immobilization is inadequate. However, EF<\/jats:styled-content>s have not been frequently used for these indications in haemophilic patients for fear of pin tract infection and bleeding. This is a retrospective therapeutic study. We describe the use of EF<\/jats:styled-content> (Orthofix uniplanar fixators) in five patients (mean age: 31.4\u00a0years; range: 10\u201352) with haemophilia A suffering from open fracture of tibia and fibula (Gustilo classification ranging from II<\/jats:styled-content> to IIIA<\/jats:styled-content>). The average time to union was 23\u00a0weeks (range: 18\u201330\u00a0weeks). Much lower levels were subsequently maintained till wound healing. The average total factor consumption was 358.30 IU<\/jats:styled-content>\u00a0kg\u22121<\/jats:sup> (range: 272\u2013421 IU<\/jats:styled-content>\u00a0kg\u22121<\/jats:sup>), administered over a period of 14.2\u00a0days (range 9\u201321). There were no major complications related to EF<\/jats:styled-content>. In summary, EF<\/jats:styled-content>s can be used safely and effectively in management of open fractures of tibia and fibula in patients with haemophilia A.<\/jats:p>","DOI":"10.1111\/hae.12538","type":"journal-article","created":{"date-parts":[[2014,12,29]],"date-time":"2014-12-29T12:14:12Z","timestamp":1419855252000},"source":"Crossref","is-referenced-by-count":7,"title":["External fixators for open fractures of tibia and fibula in patients with haemophilia A"],"prefix":"10.1111","volume":"21","author":[{"given":"J.","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery The First Affiliated Hospital of Soochow University Suzhou Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery The First Affiliated Hospital of Soochow University Suzhou Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery The First Affiliated Hospital of Soochow University Suzhou Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery The First Affiliated Hospital of Soochow University Suzhou Jiangsu China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,12,29]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2516.2002.00628.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2516.2003.00844.x"},{"key":"e_1_2_7_4_1","first-page":"41","article-title":"Grinfeld B [Orthopedic and trauma surgery in hemophilia with a case report]","volume":"36","author":"Perinovic D","year":"1982","journal-title":"Med Arh"},{"key":"e_1_2_7_5_1","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1302\/0301-620X.56B4.643","article-title":"Fracture management in patients with haemophilia","volume":"56","author":"Feil E","year":"1974","journal-title":"J Bone Joint Surg Br"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-922225"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2007.01448.x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-197207000-00025"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-197557080-00021"}],"container-title":["Haemophilia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fhae.12538","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fhae.12538","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hae.12538","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T13:24:19Z","timestamp":1695561859000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hae.12538"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12,29]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["10.1111\/hae.12538"],"URL":"https:\/\/doi.org\/10.1111\/hae.12538","archive":["Portico"],"relation":{},"ISSN":["1351-8216","1365-2516"],"issn-type":[{"value":"1351-8216","type":"print"},{"value":"1365-2516","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12,29]]}}}