{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T15:20:45Z","timestamp":1779376845420,"version":"3.53.1"},"reference-count":30,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,4,30]],"date-time":"2015-04-30T00:00:00Z","timestamp":1430352000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2015,7]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>Advanced haemophilic arthropathy of the knee is associated with progressive joint stiffness. Results after total knee arthroplasty (<jats:styled-content style=\"fixed-case\">TKA<\/jats:styled-content>) in stiff knees are considered to be inferior compared to those with less restricted preoperative range of motion (<jats:styled-content style=\"fixed-case\">ROM<\/jats:styled-content>). There is only very limited data on the results of primary <jats:styled-content style=\"fixed-case\">TKA<\/jats:styled-content> in haemophilic patients with stiff knees.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>The purpose of this retrospective study was to evaluate the clinical outcome after <jats:styled-content style=\"fixed-case\">TKA<\/jats:styled-content> performed in haemophilic patients with preoperative <jats:styled-content style=\"fixed-case\">ROM<\/jats:styled-content> of 50\u00b0 or less.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty one patients (23 knees) undergoing <jats:styled-content style=\"fixed-case\">TKA<\/jats:styled-content> with stiff knees were retrospectively evaluated. Mean follow\u2010up was 8.3\u00a0years (range, 2\u201325). Clinical assessment included <jats:styled-content style=\"fixed-case\">ROM<\/jats:styled-content>, degree of flexion contracture and complication rate. Functional evaluation and pain status were assessed using the Knee Society's Scoring System (<jats:styled-content style=\"fixed-case\">KSS<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Range of motion improved from 26.7\u00b0 preoperatively to 73.0\u00b0 postoperatively. Flexion contracture decreased from 21.7\u00b0 to 8.3\u00b0. KSS increased from 22.9 to 72.9 points. Evaluation of pain revealed a decrease from 8.4 points preoperatively to 2.1 points postoperatively. All these differences were statistically significant (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.005). The complication rate was 8.7% including one late periprosthetic infection, and one aseptic implant loosening. Nine patients who required <jats:styled-content style=\"fixed-case\">VY<\/jats:styled-content>\u2010quadricepsplasty for knee exposure developed a mean postoperative extensor lag of 7\u00b0.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Total knee arthroplasty in haemophilic patients presenting with stiff knees results in significant improvement of function and reduction in pain. Although the clinical outcome is inferior compared to nonstiff knees reported in the literature, joint replacement surgery can be successfully performed in this particular group of patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hae.12698","type":"journal-article","created":{"date-parts":[[2015,4,30]],"date-time":"2015-04-30T11:59:14Z","timestamp":1430395154000},"source":"Crossref","is-referenced-by-count":40,"title":["Outcome after total knee arthroplasty in haemophilic patients with stiff knees"],"prefix":"10.1111","volume":"21","author":[{"given":"A. C.","family":"Strauss","sequence":"first","affiliation":[{"name":"Department of Orthopaedics and Trauma Surgery University of Bonn Bonn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Schmolders","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Trauma Surgery University of Bonn Bonn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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