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Low bone mineral density (<jats:styled-content style=\"fixed-case\">BMD<\/jats:styled-content>) is one such co\u2010morbidity where the incidence not only increases with age, but also occurs with greater frequency in <jats:styled-content style=\"fixed-case\">PWH<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To review risk factors for low <jats:styled-content style=\"fixed-case\">BMD<\/jats:styled-content>, and strategies to promote bone health and identify patients who would benefit from screening for osteoporosis and subsequent treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A narrative review of the literature was performed in <jats:styled-content style=\"fixed-case\">MEDLINE<\/jats:styled-content> with keywords haemophilia, bone density, osteoporosis and fracture. Reference lists of retrieved articles were also reviewed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Low <jats:styled-content style=\"fixed-case\">BMD<\/jats:styled-content> occurs more commonly in <jats:styled-content style=\"fixed-case\">PWH<\/jats:styled-content> than the general population and is most likely the result of a combination of risk factors.\u00a0 Steps to promote bone health include preventing haemarthrosis, encouraging regular exercise, adequate vitamin D and calcium intake, and avoiding tobacco and excessive alcohol intake. Adults 50 years of age and older with haemophilia and those younger than 50 years with a fragility fracture or increased fracture risk based on <jats:styled-content style=\"fixed-case\">FRAX<\/jats:styled-content> (The Fracture Risk Assessment Tool), regardless of haemophilia severity, should be screened for low <jats:styled-content style=\"fixed-case\">BMD<\/jats:styled-content> using dual x\u2010ray absorptiometry (<jats:styled-content style=\"fixed-case\">DXA<\/jats:styled-content>). Once osteoporosis is diagnosed based on <jats:styled-content style=\"fixed-case\">DXA<\/jats:styled-content>, fracture risk should guide treatment. Currently, treatment is similar to those without haemophilia and most commonly includes bisphosphonates.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Haemophilia care providers should promote adequate bone formation during childhood and reduce bone loss during adulthood as well as identify patients with low <jats:styled-content style=\"fixed-case\">BMD<\/jats:styled-content> that would benefit from therapy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hae.12736","type":"journal-article","created":{"date-parts":[[2015,7,14]],"date-time":"2015-07-14T13:56:20Z","timestamp":1436882180000},"page":"568-577","source":"Crossref","is-referenced-by-count":36,"title":["Bone health in persons with haemophilia"],"prefix":"10.1111","volume":"21","author":[{"given":"C. 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