{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:51:07Z","timestamp":1787014267928,"version":"build-2736575974"},"reference-count":39,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,11,16]],"date-time":"2016-11-16T00:00:00Z","timestamp":1479254400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Viscosupplementation can improve function in haemophilia patients. Viscosupplementation results can be improved by prior joint lavage and triamcinolone administration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To objectively assess whether viscosupplementation and associated triamcinolone use in patients with severe haemophilic arthropathy following joint lavage improves force and balance and reduces bleeding events.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Fourteen patients with haemophilic knee arthritis with and without the involvement of other joints underwent joint lavage and subsequent injections of Hylan G\u2010F20 and triamcinolone into all affected joints. Patients were evaluated with NeuroCom\n                      <jats:sup>\u00ae<\/jats:sup>\n                      force and balance platforms using the step\u2010up\u2010and\u2010over task (\n                      <jats:styled-content style=\"fixed-case\">STP<\/jats:styled-content>\n                      ), sit\u2010to\u2010stand test (\n                      <jats:styled-content style=\"fixed-case\">STS<\/jats:styled-content>\n                      ), one\u2010leg stance (\n                      <jats:styled-content style=\"fixed-case\">UNI<\/jats:styled-content>\n                      ) and weight\u2010bearing squat (\n                      <jats:styled-content style=\"fixed-case\">WBS<\/jats:styled-content>\n                      ) at baseline and at 1, 3, 6 and 12 months after the procedure. Bleeding events in the year prior to and the year after the procedure were analysed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Sixteen knees, 15 ankles, eight elbows and one shoulder were treated. The\n                      <jats:styled-content style=\"fixed-case\">STP<\/jats:styled-content>\n                      results indicated improvements in the lift\u2010up indices (right leg) at all time points evaluated (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.03). The\n                      <jats:styled-content style=\"fixed-case\">STS<\/jats:styled-content>\n                      results revealed coupled improvement in weight transfer and the rising index for up to a year (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.02). Balance (\n                      <jats:styled-content style=\"fixed-case\">UNI<\/jats:styled-content>\n                      ) with eyes open or closed improved in all evaluations. The\n                      <jats:styled-content style=\"fixed-case\">WBS<\/jats:styled-content>\n                      results revealed improvements at all degrees of flexion (0,\n                      <jats:italic>P<\/jats:italic>\n                      = 0.003; 30\u00b0,\n                      <jats:italic>P<\/jats:italic>\n                      = 0.001; 60\u00b0,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001 and 90\u00b0,\n                      <jats:italic>P<\/jats:italic>\n                      &lt; 0.001). The numbers of total and traumatic bleeding events were reduced (\n                      <jats:italic>P<\/jats:italic>\n                      = 0.04).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Joint lavage followed by injections of triamcinolone and Hylan G\u2010F20 improved balance, function and bleeding events in severe haemophilic arthropathy patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hae.13115","type":"journal-article","created":{"date-parts":[[2016,11,16]],"date-time":"2016-11-16T14:34:26Z","timestamp":1479306866000},"source":"Crossref","is-referenced-by-count":15,"title":["Joint lavage followed by viscosupplementation and triamcinolone in patients with severe haemophilic arthropathy: objective functional results"],"prefix":"10.1111","volume":"23","author":[{"given":"M. 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