{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T16:38:06Z","timestamp":1778776686170,"version":"3.51.4"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,3,17]],"date-time":"2017-03-17T00:00:00Z","timestamp":1489708800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:sec><jats:title>Introduction<\/jats:title><jats:p>There are two general surgical approaches for operative treatment of end\u2010stage haemophilic ankle arthropathy: ankle arthrodesis and total ankle replacement (<jats:styled-content style=\"fixed-case\">TAR<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study was to determine intraoperative and postoperative complications and evaluate the mid\u2010term clinical and radiographic outcomes of <jats:styled-content style=\"fixed-case\">TAR<\/jats:styled-content> in patients with haemophilic arthropathy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Fourteen patients with a mean age of 51.4 \u00b1 10.2 years (range = 32.9\u201363.7) were treated for end\u2010stage haemophilic ankle arthropathy. Nine procedures were primary arthroplasties, five procedures were conversions of painful ankle arthrodesis to <jats:styled-content style=\"fixed-case\">TAR<\/jats:styled-content>. The mean duration of follow\u2010up was 5.8 \u00b1 2.3 years (range = 2.0\u20139.2). Component stability and alignment was assessed with weight\u2010bearing radiographs. Clinical assessment was performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>One patient sustained an intraoperative medial malleolar fracture. In two patients, delayed wound healing was observed. In one patient, open arthrolysis was performed due to painful arthrofibrosis. Both components were neutrally aligned. Visual analogue scale (VAS) significantly decreased from 8.5 \u00b1 0.9 (range = 8\u201310) to 1.3 \u00b1 1.6 (range = 0\u20136). Significant functional improvement including range of motion (ROM) and American Orthopaedic Foot and Ankle Society (AOFAS) hindfoot score was observed. The summarized components of the <jats:styled-content style=\"fixed-case\">SF<\/jats:styled-content>\u201036 physical and mental outcomes score significantly improved at the latest follow\u2010up. Complication rates and clinical\/radiographic outcomes were comparable in patients with primary <jats:styled-content style=\"fixed-case\">TAR<\/jats:styled-content> and conversion of ankle arthrodesis to <jats:styled-content style=\"fixed-case\">TAR<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The mid\u2010term results following <jats:styled-content style=\"fixed-case\">TAR<\/jats:styled-content> or a conversion procedure in patients with haemophilic arthropathy are encouraging. However, for postoperative success, access to an experienced, multidisciplinary team including a haematologist is mandatory.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hae.13200","type":"journal-article","created":{"date-parts":[[2017,3,17]],"date-time":"2017-03-17T14:02:42Z","timestamp":1489759362000},"source":"Crossref","is-referenced-by-count":15,"title":["Total ankle replacement in patients with haemophilic arthropathy: primary arthroplasty and conversion of painful ankle arthrodesis to arthroplasty"],"prefix":"10.1111","volume":"23","author":[{"given":"M.","family":"Preis","sequence":"first","affiliation":[{"name":"Department of Orthopaedics Aukammklinik  Wiesbaden Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Bailey","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics University of Utah  Salt Lake City UT USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Jacxsens","sequence":"additional","affiliation":[{"name":"Harold K. 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