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Due to its physical and psychological benefits, sport is increasingly re\u2010commended for haemophilic patients. Evidence on the cost\u2010effectiveness of sports therapy is still lacking.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study was to determine the cost\u2010effectiveness of a 6\u2010month programmed sports therapy (<jats:styled-content style=\"fixed-case\">PST<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The cost\u2010effectiveness of the 6\u2010month <jats:styled-content style=\"fixed-case\">PST<\/jats:styled-content> was assessed from a societal perspective alongside a <jats:styled-content style=\"fixed-case\">RCT<\/jats:styled-content> using cost\u2010utility analysis. The analysis included 50 PwH with moderate\u2010to\u2010severe haemophilia A and B and a training period over 6\u00a0months. The health\u2010related quality of life was measured with the EuroQoL\u2010domain questionnaire. Resource utilization was assessed by questionnaire before and after the intervention. A cost\u2010effectiveness acceptability curve was constructed, and sensitivity analyses were performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>During the 6\u2010month study period, mean adjusted total healthcare costs were lower (mean difference: \u221222\u00a0805 <jats:styled-content style=\"fixed-case\">EUR<\/jats:styled-content>; 95%\u2010<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: \u221273\u00a0944\u201048\u00a0463; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.59) and the number of <jats:styled-content style=\"fixed-case\">QALY<\/jats:styled-content>s was higher in the intervention group (mean difference: 0.3733; 95%\u2010<jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>: 0.0014\u20100.0573; <jats:italic>P<\/jats:italic>\u00a0=\u00a0.04). The probability of an incremental cost\u2010effectiveness ratio &lt;50\u00a0000 <jats:styled-content style=\"fixed-case\">EUR<\/jats:styled-content> per <jats:styled-content style=\"fixed-case\">QALY<\/jats:styled-content> was 71%. The performed sensitivity analysis confirmed these results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Results showed that the <jats:styled-content style=\"fixed-case\">PST<\/jats:styled-content> is effective in terms of a significant gain of <jats:styled-content style=\"fixed-case\">QALY<\/jats:styled-content>s. Furthermore, results weakly indicate the potential of the <jats:styled-content style=\"fixed-case\">PST<\/jats:styled-content> to reduce healthcare costs. Future studies should expand the observation period to have a closer look at the influence of <jats:styled-content style=\"fixed-case\">PST<\/jats:styled-content> on lifetime costs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hae.13459","type":"journal-article","created":{"date-parts":[[2018,3,30]],"date-time":"2018-03-30T07:52:52Z","timestamp":1522396372000},"page":"385-394","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Cost\u2010utility of a six\u2010month programmed sports therapy (<scp>PST<\/scp>) in patients with haemophilia"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3451-7847","authenticated-orcid":false,"given":"J.","family":"Koeberlein\u2010Neu","sequence":"first","affiliation":[{"name":"Center for Health Economics and Health Services Research University of Wuppertal  Wuppertal Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Runkel","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine University of Wuppertal  Wuppertal Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0935-2526","authenticated-orcid":false,"given":"T.","family":"Hilberg","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine University of Wuppertal  Wuppertal Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,3,30]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2011.04.030"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2516.1999.0050s1053.x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2006.01268.x"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199710000-00017"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2011.02607.x"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-200001000-00009"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2008.01860.x"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2516.2001.00563.x"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/hae.12909"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/hae.12485"},{"key":"e_1_2_10_12_1","first-page":"118","article-title":"T H. 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