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However, delays in providing those diagnosis and appropriate management are often reported despite increased availability of genetic techniques and improved awareness that carriers may have bleeding experiences. Women with von Willebrand disease (<jats:styled-content style=\"fixed-case\">VWD<\/jats:styled-content>) and rare factor deficiencies (<jats:styled-content style=\"fixed-case\">RFD<\/jats:styled-content>) may bleed during pregnancy and following childbirth and in some cases may experience adverse foetal\/neonatal outcomes. This review describes the evolution of practice, unmet needs and options for both girls and women in families with haemophilia as well as the clinical and laboratory characteristics during pregnancy and recommendation for the delivery and the postpartum follow\u2010up in women with <jats:styled-content style=\"fixed-case\">VWD<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">RFD<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/hae.13502","type":"journal-article","created":{"date-parts":[[2018,5,31]],"date-time":"2018-05-31T22:57:23Z","timestamp":1527807443000},"page":"29-36","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":53,"title":["Women with bleeding disorders"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5429-8437","authenticated-orcid":false,"given":"C.","family":"Hermans","sequence":"first","affiliation":[{"name":"Haemostasis and Thrombosis Unit Division of Haematology Cliniques universitaires Saint\u2010Luc  Brussels Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9372-3184","authenticated-orcid":false,"given":"R.","family":"Kulkarni","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Human Development Michigan State University  East Lansing MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,5,21]]},"reference":[{"key":"e_1_2_17_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2004.00955.x"},{"key":"e_1_2_17_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.1975.tb01859.x"},{"key":"e_1_2_17_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01811464"},{"key":"e_1_2_17_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2008.01974.x"},{"key":"e_1_2_17_6_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-09-3879"},{"key":"e_1_2_17_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.24709"},{"key":"e_1_2_17_8_1","first-page":"135","article-title":"Sex chromatin and gene action in the mammalian X\u2010chromosome","volume":"14","author":"Lyon MF","year":"1962","journal-title":"Am J Hum Genet"},{"key":"e_1_2_17_9_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1613833"},{"key":"e_1_2_17_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2010.02426.x"},{"key":"e_1_2_17_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2009.02108.x"},{"key":"e_1_2_17_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/hae.13298"},{"key":"e_1_2_17_13_1","unstructured":"https:\/\/www.francecoag.org\/SiteWebPublic\/html\/accueil.html.2018."},{"key":"e_1_2_17_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2007.01649.x"},{"key":"e_1_2_17_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.1320370134"},{"key":"e_1_2_17_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10897-015-9834-8"},{"key":"e_1_2_17_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/hae.12269"},{"key":"e_1_2_17_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2011.02561.x"},{"key":"e_1_2_17_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2010.02315.x"},{"key":"e_1_2_17_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2011.02558.x"},{"key":"e_1_2_17_21_1","volume-title":"The Diagnosis, Evaluation and Management of Von Willebrand Disease","author":"NHLBI von Willebrand Disease Expert Panel","year":"2017"},{"key":"e_1_2_17_22_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1616060"},{"key":"e_1_2_17_23_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-08-532820"},{"key":"e_1_2_17_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2012.04653.x"},{"key":"e_1_2_17_25_1","unstructured":"Centers for Disease Control and Prevention.Community Counts HTC Population Profile data through 9\/29\/2017.https:\/\/www.cdc.gov\/ncbddd\/hemophilia\/communitycounts\/data-community-counts.html. 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