{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:51:11Z","timestamp":1787014271322,"version":"build-2736575974"},"reference-count":35,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,6,6]],"date-time":"2018-06-06T00:00:00Z","timestamp":1528243200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2018,7]]},"abstract":"\n Introduction<\/jats:title>\n \n Haemophilia is one of the most common inherited bleeding disorders in the Emergency Department (\n ED<\/jats:styled-content>\n ). The most dangerous site of bleeding is the central nervous system.\n <\/jats:p>\n <\/jats:sec>\n \n Aims<\/jats:title>\n \n To describe the characteristics of haemophiliacs arrived to our\n ED<\/jats:styled-content>\n following a head trauma and to analyse the incidence of intracranial haemorrhage (\n ICH<\/jats:styled-content>\n ).\n <\/jats:p>\n <\/jats:sec>\n \n Materials and Methods<\/jats:title>\n \n Retrospective, analytical, observational study, conducted in a Paediatric\n ED<\/jats:styled-content>\n . We included haemophilic patients aged from birth to 16\u00a0years who consulted after a head trauma over a 6\u2010year period. Data collected included age, type of haemophilia and head trauma, symptoms, prophylaxis status,\n CT<\/jats:styled-content>\n imaging, treatment and number of visits to the\n ED<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n About 46 males and 85 episodes were analysed. The median age was 2.38\u00a0years. Severe haemophilia A was the most frequent type of disease (50%). All head injuries were mild, and the most frequent mechanism was a collision with an object (38.8%). In 62 episodes (72.9%) the patients were asymptomatic. The rest 23 events had symptomatology, being the most common headache (26%), emesis (21.7%) and drowsiness (17.4%). Head\n CT<\/jats:styled-content>\n was obtained in 31 episodes, founding altered results in 10 (6 of them corresponding to\n ICH<\/jats:styled-content>\n ). All the patients with\n ICH<\/jats:styled-content>\n had symptomatology. About 37 episodes required admission.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n Intracranial haemorrhage is one of the most dangerous events in haemophiliacs and it may occur after a head trauma. Our study suggests that, in case of head trauma,\n CT<\/jats:styled-content>\n must be obtained in symptomatic patients and in those with additional risk factors. Asymptomatic patients must have prolonged observation.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/hae.13526","type":"journal-article","created":{"date-parts":[[2018,6,6]],"date-time":"2018-06-06T05:02:18Z","timestamp":1528261338000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Head trauma in the haemophilic child and management in a paediatric emergency department: Descriptive study"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4866-6656","authenticated-orcid":false,"given":"P.","family":"Garc\u00eda S\u00e1nchez","sequence":"first","affiliation":[{"name":"Paediatric Emergency Department and Hematology Department La Paz University Hospital Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. \u00c1.","family":"Molina Guti\u00e9rrez","sequence":"additional","affiliation":[{"name":"Paediatric Emergency Department and Hematology Department La Paz University Hospital Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Mart\u00edn S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Paediatric Emergency Department and Hematology Department La Paz University Hospital Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Inisterra Viu","sequence":"additional","affiliation":[{"name":"Paediatric Emergency Department and Hematology Department La Paz University Hospital Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Garc\u00eda Garc\u00eda","sequence":"additional","affiliation":[{"name":"Paediatric Emergency Department and Hematology Department La Paz University Hospital Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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