{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T06:15:52Z","timestamp":1790748952696,"version":"4.1.0"},"reference-count":44,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,7,10]],"date-time":"2018-07-10T00:00:00Z","timestamp":1531180800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:p>Haemophilia is characterized by a congenital deficiency of clotting factor <jats:styled-content style=\"fixed-case\">VIII<\/jats:styled-content> or <jats:styled-content style=\"fixed-case\">IX<\/jats:styled-content>. One of the consequences of haemophilia is joint bleedings. Repetitive haemathroses induce cartilage damage and chronic synovitis leading to joint deterioration, and to definitive haemophilic arthropathy which is source of walking disability. Three\u2010dimension gait analysis (3<jats:styled-content style=\"fixed-case\">DGA<\/jats:styled-content>) appears particularly relevant in the case of haemophilia because it allows an evaluation of several joints in weight\u2010bearing situations. The purpose of this study was to review the interest and the contribution of 3<jats:styled-content style=\"fixed-case\">DGA<\/jats:styled-content> in the management of patients with haemophilia. The greatest interest of gait analysis would be to detect early walking changes with a non\u2010invasive and well\u2010tolerated examination, especially in paediatric population. In adulthood, this technic may be also useful to help detect walking worsening in patients known to have already arthropathy. However, it takes time to realize and needs expensive equipment, which limits its possibility of routine use. Although generalizations of these results remain difficult, especially to compare patients with haemophilia to normal population. Indeed, in the studies, patient groups are small and usually heterogeneous in terms of age and target joints. It certainly results of the rarity of the disease. So, it could be interesting to perform a study with a larger cohort in order to allow subgroup analysis, helping to define clearly the place of 3<jats:styled-content style=\"fixed-case\">DGA<\/jats:styled-content> in the strategy of haemophilia evaluation.<\/jats:p>","DOI":"10.1111\/hae.13563","type":"journal-article","created":{"date-parts":[[2018,7,10]],"date-time":"2018-07-10T11:16:55Z","timestamp":1531221415000},"page":"703-710","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":23,"title":["Clinical relevance of 3D gait analysis in patients with haemophilia"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8139-814X","authenticated-orcid":false,"given":"A.","family":"Fouasson\u2010Chailloux","sequence":"first","affiliation":[{"name":"CHU Nantes Physical Medicine and Rehabilitation Center  Nantes France"},{"name":"Inserm UMR 1229 RMeS, Regenerative Medicine and Skeleton Universit\u00e9 de 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