{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T16:01:02Z","timestamp":1760889662041,"version":"3.37.3"},"reference-count":42,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2018,7,13]],"date-time":"2018-07-13T00:00:00Z","timestamp":1531440000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The previous studies have described only closed\u2010wedge high tibial osteotomy (<jats:styled-content style=\"fixed-case\">HTO<\/jats:styled-content>) in haemophilic arthropathy (<jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content>).<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>The purpose of this study was to evaluate clinical and radiographic results after open\u2010wedge <jats:styled-content style=\"fixed-case\">HTO<\/jats:styled-content> in <jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content> with varus knee deformity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We included 13 open\u2010wedge <jats:styled-content style=\"fixed-case\">HTO<\/jats:styled-content>s in <jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content> performed between 2005 and 2016. The mean age of patients was 28.9\u00a0years. Visual analogue scale (<jats:styled-content style=\"fixed-case\">VAS<\/jats:styled-content>), Western Ontario and McMaster Universities (<jats:styled-content style=\"fixed-case\">WOMAC<\/jats:styled-content>), and range of motion (<jats:styled-content style=\"fixed-case\">ROM<\/jats:styled-content>) indices were assessed. Any complications or requirements for total knee arthroplasty (<jats:styled-content style=\"fixed-case\">TKA<\/jats:styled-content>) were investigated. Mechanical axis (<jats:styled-content style=\"fixed-case\">MA<\/jats:styled-content>), minimal joint space width (<jats:styled-content style=\"fixed-case\">mJSW<\/jats:styled-content>) and Pettersson score were measured. Bone union rates at 3 and 6\u00a0months postoperative were evaluated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>VAS improved from 5.1 to 2.4 (<jats:italic>P\u00a0<\/jats:italic>&lt;\u00a0.001). <jats:styled-content style=\"fixed-case\">WOMAC<\/jats:styled-content> was 66.5 preoperatively, and 26.6 postoperatively (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001). Pre\u2010 and postoperative <jats:styled-content style=\"fixed-case\">ROM<\/jats:styled-content> did not differ significantly. There were no cases of <jats:styled-content style=\"fixed-case\">HTO<\/jats:styled-content> converted to <jats:styled-content style=\"fixed-case\">TKA<\/jats:styled-content>, but one case of <jats:styled-content style=\"fixed-case\">HTO<\/jats:styled-content> required <jats:styled-content style=\"fixed-case\">TKA<\/jats:styled-content> 152\u00a0months postoperative. No complications were observed. The <jats:styled-content style=\"fixed-case\">MA<\/jats:styled-content> was corrected from varus 5.1\u00b0 to valgus 1.2\u00b0 (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001). Pre\u2010 and postoperative <jats:styled-content style=\"fixed-case\">mJSW<\/jats:styled-content> did not significantly differ. Pettersson score improved from 3.84 to 2.47 (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a0.001). The bone union rates at the osteotomy gap were 45.2% and 67.8% at 3 and 6\u00a0months postoperative.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Open\u2010wedge <jats:styled-content style=\"fixed-case\">HTO<\/jats:styled-content> should be considered in cases of <jats:styled-content style=\"fixed-case\">HA<\/jats:styled-content> with varus deformity in young haemophilic patients, even though inflammatory arthritis is not an optimal indication for this procedure. It can be an appropriate treatment with respect to the choice to postpone <jats:styled-content style=\"fixed-case\">TKA<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hae.13566","type":"journal-article","created":{"date-parts":[[2018,7,13]],"date-time":"2018-07-13T14:37:25Z","timestamp":1531492645000},"page":"792-799","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Clinical and radiologic results after open\u2010wedge high tibial osteotomy in haemophilic knee arthropathy with varus deformity"],"prefix":"10.1111","volume":"24","author":[{"given":"Y. J.","family":"Cho","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery College of Medicine Kyung Hee University  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. J.","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery College of Medicine Kyung Hee University  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. H.","family":"Rhyu","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery College of Medicine Kyung Hee University  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T. S.","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery College of Medicine Kyung Hee University  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8297-6872","authenticated-orcid":false,"given":"C. H.","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Medicine Graduate School Kyung Hee University  Seoul Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,7,13]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2516.2000.00044.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2012.02909.x"},{"key":"e_1_2_9_4_1","first-page":"342","article-title":"[Orthopedic problems in hemophilia. 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