{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T04:43:58Z","timestamp":1788669838777,"version":"build-2803163510"},"reference-count":18,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2020,6,12]],"date-time":"2020-06-12T00:00:00Z","timestamp":1591920000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Haemophilic pseudotumour (HP) is an encapsulated haematoma in patients with haemophilia (PWH) which has a tendency to progress and produce clinical symptoms related to its anatomical location.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To show the experience of one surgeon who has been using mini\u2010invasive technique to treat pseudotumours of limbs in PWH with and without inhibitors at one centre for 28\u00a0years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Materials and Methods<\/jats:title><jats:p>Thirty\u2010three patients with 39 HP were treated. All patients had haemophilia A. Twenty\u2010four patients had no inhibitors (72.8%), and 9 had inhibitors (27.2%). The mean follow\u2010up was 16\u00a0years (1\u201025). All patients had x\u2010rays and MRIs. All of them received Buenos Aires protocol as conservative treatment for 6\u00a0weeks. MRIs were repeated after 6\u00a0weeks\u2019 treatment to assess response to treatment.<\/jats:p><jats:p>Surgery was performed in patients who did not respond to conservative treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After Buenos Aires protocol, four pseudotumours did not shrink (10.24%), 33 (84.61%) shrank, and two (5.12%) healed. Thirty\u2010seven pseudotumours had surgery, 35 pseudotumours (94.59%) healed with minimally invasive treatment, and two did not heal (5.41%).<\/jats:p><jats:p>No infection was observed with this treatment. The mortality rate for the series was 0%.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The minimally invasive treatment of pseudotumours was effective in 95% of the cases and resulted in no mortality in this series after 28\u00a0years.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hae.14069","type":"journal-article","created":{"date-parts":[[2020,6,12]],"date-time":"2020-06-12T12:13:27Z","timestamp":1591964007000},"page":"694-700","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Minimally invasive surgery for haemophilic pseudotumour of the limbs: 28 years of experience"],"prefix":"10.1111","volume":"26","author":[{"given":"Horacio Alberto","family":"Caviglia","sequence":"first","affiliation":[{"name":"Department of Orthopaedics and Traumatology General Hospital Dr. Juan A. Fern\u00e1ndez Buenos Aires Argentina"},{"name":"Haemophilia Foundation Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3042-730X","authenticated-orcid":false,"given":"Ana Laura","family":"Douglas Price","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology General Hospital Dr. Juan A. Fern\u00e1ndez Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo","family":"Cambiaggi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology General Hospital Dr. Juan A. Fern\u00e1ndez Buenos Aires Argentina"},{"name":"Haemophilia Foundation Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Egle","family":"Honorat","sequence":"additional","affiliation":[{"name":"Haemophilia Foundation Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pablo","family":"Salgado","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology General Hospital Dr. Juan A. Fern\u00e1ndez Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo Alberto","family":"Galatro","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology General Hospital Dr. Juan A. Fern\u00e1ndez Buenos Aires Argentina"},{"name":"Haemophilia Foundation Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,6,12]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-197557080-00020"},{"key":"e_1_2_6_3_1","first-page":"165","volume-title":"Hemophilia and von Willebrand's Disease in the 1990s","author":"Tezanos Pinto M","year":"1991"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/798649"},{"key":"e_1_2_6_5_1","volume-title":"Treatment of haemophilia and other coagulation disorders","author":"Gunning A","year":"1966"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/1076029610366433"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2516.2002.00577.x"},{"key":"e_1_2_6_8_1","first-page":"257","article-title":"The hemophilic pseudotumor","volume":"324","author":"Gilbert MS","year":"1990","journal-title":"Prog Clin Biol Res"},{"key":"e_1_2_6_9_1","first-page":"353","volume-title":"Ortopedia e Fisioterapia em Hemofilia","author":"Caviglia H","year":"2013"},{"key":"e_1_2_6_10_1","volume-title":"Hemopillia in children. 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