{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T19:50:29Z","timestamp":1778615429221,"version":"3.51.4"},"reference-count":32,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2020,8,7]],"date-time":"2020-08-07T00:00:00Z","timestamp":1596758400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To compare foot joint kinetics and energetics in male paediatric boys with and without blood\u2010induced ankle joint destruction to these of matched control groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional study was conducted in which 3D gait analysis data were collected from thirty\u2010five male children (6\u201021\u00a0years) with severe or moderate haemophilia and twenty\u2010six typically developing boys. Structural integrity of the tarsal foot joints of all haemophilic patients was assessed using the IPSG\u2010MRI scale. All participants walked barefoot while adopting a physiological gait pattern. Three subgroups were created based on the IPSG\u2010MRI scores: a group with no joint involvement (HealthyHaemo), with uni\u2010 or bilaterally involvement (PathoHaemo) and with only unilaterally involvement (Haemo_Unilateral_Patho).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The PathoHaemo group presented a significant lower Lisfranc peak dorsiflexion angular velocity (34.7\u00b0\/s vs 71.4\u00b0\/s,<jats:italic>P<\/jats:italic>\u00a0=\u00a0.000, Cohen d\u00a0=\u00a01.31) and a significantly higher Lisfranc peak plantarflexion angular velocity (\u2212130.5\u00b0\/s vs \u221251.8\u00b0\/s,<jats:italic>P<\/jats:italic>\u00a0=\u00a0.000, Cohen d\u00a0=\u00a00.98) compared to the control group. The Haemo_Unilateral_Patho side had a significant higher Chopart peak dorsiflexion angular velocity compared to the Haemo_Unilateral_Healthy side (41.7\u00b0\/s vs 31.9\u00b0\/s,<jats:italic>P<\/jats:italic>\u00a0=\u00a0.002, Cohen d\u00a0=\u00a01.16).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>No evidence for mild and severe gait deviations could be demonstrated. Internal moments, used as a surrogate measure of joint loading, quantified by the multi\u2010segment foot model were found to be similar within the three subanalyses. We suggest that the ongoing musculoskeletal development in children compensates for structural damage to the ankle joint.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hae.14128","type":"journal-article","created":{"date-parts":[[2020,8,8]],"date-time":"2020-08-08T07:00:51Z","timestamp":1596870051000},"page":"907-915","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Paediatric patients with blood\u2010induced ankle joint arthritis demonstrate physiological foot joint mechanics and energetics during walking"],"prefix":"10.1111","volume":"26","author":[{"given":"Dorien","family":"Tijskens","sequence":"first","affiliation":[{"name":"Department of Rehabilitation Sciences Musculoskeletal Rehabilitation Research Group KULeuven Heverlee 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