{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T15:47:40Z","timestamp":1765295260373},"reference-count":39,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T00:00:00Z","timestamp":1630972800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Haemophilic arthropathy results in a restricted range of motion and pain that often affects gait. The effect of these gait changes on spinal posture has not been studied.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate whether the altered joint situation in patients with haemophilia (PwH) leads to compensatory mechanisms evident in the trunk and spine, considering static and dynamic conditions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>PwH and healthy controls (20\u201365 years) were examined using rasterstereography in a controlled cohort study. Analysis was performed in static and dynamic conditions in regard to gait phases. Joint status was determined using the Haemophilia Joint Health Score (HJHS).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Static measurements showed no group differences in PwH (<jats:italic>n<\/jats:italic> = 40) compared to healthy controls (<jats:italic>n<\/jats:italic> = 40) except pelvic torsion (median [25%\u2010quartile;75%\u2010quartile]: \u20101.9[\u20103.2;.9]\u00b0 vs. .5[\u20101.1;1.9]\u00b0; <jats:italic>P<\/jats:italic> = .007). In contrast, under dynamic conditions PwH showed significantly higher trunk inclination and lower apex lumbar lordosis in all gait phases. Additionally, pelvic torsion was increased in mid stance and terminal swing. Considering joint status, PwH had a higher global HJHS (23.5[13.0;30.0] vs. 3.0[1.0;5.0]; <jats:italic>P<\/jats:italic>&lt;.001). A significant moderate correlation was shown between the HJHS mobility score and spine parameters (r = .228\u2013.588; <jats:italic>P<\/jats:italic>&lt;.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Degenerative joint changes in PwH lead to altered spine posture during gait. A reason could be the reduced mobility in the affected joint. Changes in spinal and pelvic posture lead to higher structural burdens; therefore, clinicians should focus on posture of spinal column during gait in daily treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hae.14406","type":"journal-article","created":{"date-parts":[[2021,9,7]],"date-time":"2021-09-07T18:01:12Z","timestamp":1631037672000},"update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Changes of static and dynamic spine alignment in patients with severe haemophilia"],"prefix":"10.1111","volume":"27","author":[{"given":"Jamil","family":"Hmida","sequence":"first","affiliation":[{"name":"Department of Sports Medicine University of Wuppertal  Wuppertal Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Hilberg","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine University of Wuppertal  Wuppertal Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steffen","family":"Kr\u00fcger","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine University of Wuppertal  Wuppertal Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom R.","family":"Jansen","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Trauma Surgery University of Bonn  Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georg","family":"Goldmann","sequence":"additional","affiliation":[{"name":"Institute for Experimental Haematology and Transfusion Medicine University of Bonn  Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Oldenburg","sequence":"additional","affiliation":[{"name":"Institute for Experimental Haematology and Transfusion Medicine University of Bonn  Bonn Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dieter 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