{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,21]],"date-time":"2026-05-21T20:37:37Z","timestamp":1779395857638,"version":"3.53.1"},"reference-count":17,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,11,20]],"date-time":"2021-11-20T00:00:00Z","timestamp":1637366400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Oral health is an important component of care at haemophilia treatment centres (HTCs). Correlations between oral health and inflammation suggest that proper oral health may improve joint health.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate the dental habits, needs, and oral health status of paediatric patients with bleeding disorders, and identify predicters of poor oral health.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>From May 2016 to October 2017, consecutive paediatric HTC patients completed a 14\u2010question survey and were examined by dental professionals. Descriptive analyses, chi\u2010square tests and logistic regression models identified characteristics associated with four main dental outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Evaluations from 226 consecutive patients (age 1\u201320 years) were included. Diagnoses included haemophilia A and B (64%), von Willebrand disease (25%) and other bleeding disorders (13%). Nearly half of patients reported not brushing their teeth twice a day (44%). One\u2010quarter of patients did not currently have a dentist (27%), and 15% reported specific challenges with access to dental care. Oral screening demonstrated significant pathology: 89% of patients had plaque accumulation, 37% had gingivitis and 8% had lesions suggestive of dental caries. Multivariate analysis revealed that having a primary caregiver with active decay was associated with significantly higher rates of suspicious lesions (OR 4.34, CI 1.41\u201013.35) and gingival erythema (OR 3.44, CI 1.63\u20107.25) and lower rates of twice daily teeth brushing (OR\u00a0.17, CI .08\u2010.37).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Children with bleeding disorders commonly have significant dental pathology and report obstacles to dental care, posing the potential risk for morbidity. Primary caregiver dental health is strongly associated with dental pathology in children.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hae.14457","type":"journal-article","created":{"date-parts":[[2021,11,20]],"date-time":"2021-11-20T17:17:36Z","timestamp":1637428656000},"page":"73-79","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Dental habits and oral health in children and adolescents with bleeding disorders: A single\u2010institution cross\u2010sectional study"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8117-1239","authenticated-orcid":false,"given":"Megan C.","family":"Brown","sequence":"first","affiliation":[{"name":"Emory University  Atlanta GA USA"},{"name":"Children's Healthcare of Atlanta  Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Hastie","sequence":"additional","affiliation":[{"name":"University of California San Diego  San Diego CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carol","family":"Shumake","sequence":"additional","affiliation":[{"name":"Children's Healthcare of Atlanta  Atlanta GA USA"},{"name":"West Georgia Family Dentistry  Douglasville GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brittany","family":"Waters","sequence":"additional","affiliation":[{"name":"Children's Healthcare of Atlanta  Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Robert F.","family":"Sidonio","sequence":"additional","affiliation":[{"name":"Emory University  Atlanta GA USA"},{"name":"Children's Healthcare of Atlanta  Atlanta GA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,11,20]]},"reference":[{"issue":"4","key":"e_1_2_8_2_1","first-page":"127","article-title":"Hemophilia and oral health","volume":"16","author":"Zaliuniene R","year":"2014","journal-title":"Stomatologija"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/scd.12189"},{"issue":"2","key":"e_1_2_8_4_1","first-page":"437","article-title":"Mortality among males with hemophilia: relations with source of medical care. The Hemophilia Surveillance System Project Investigators","volume":"96","author":"Soucie JM","year":"2000","journal-title":"Blood"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/hae.12434"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2011.02716.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-2391(03)00739-0"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/2231-0762.149022"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0528.1994.tb02049.x"},{"issue":"5","key":"e_1_2_8_10_1","first-page":"E157","article-title":"American Academy of Pediatric D. Guideline on caries\u2010risk assessment and management for infants, children, and adolescents","volume":"35","year":"2013","journal-title":"Pediatr Dent"},{"key":"e_1_2_8_11_1","article-title":"Dental habits in children and adolescents with bleeding disorders","author":"Brown MCHE","year":"2021","journal-title":"REDCap"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034509360010"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/0009922813483876"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-0361.2003.tb00572.x"},{"key":"e_1_2_8_15_1","unstructured":"Dentists AsP.AAPD Encourages Parents to \u201cGet it Done in Year One\u201d for a Lifetime of Healthy Smiles 2010.http:\/\/www.aapd.org\/aapd_encourages_parents_to_\u201cget_it_done_in_year_one\u201d_for_a_lifetime_of_healthy_smiles\/"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/hae.12325"},{"issue":"6","key":"e_1_2_8_17_1","first-page":"180","article-title":"Guideline on Behavior Guidance for the Pediatric Dental Patient","volume":"37","author":"Subcommittee CACBM","year":"2015","journal-title":"American Academy of Pediatric Dentistry Clinical Practice Guidelines Reference Manual"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.4172\/2375-4494.1000356"}],"container-title":["Haemophilia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hae.14457","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/hae.14457","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hae.14457","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T18:52:58Z","timestamp":1692989578000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hae.14457"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,20]]},"references-count":17,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022,1]]}},"alternative-id":["10.1111\/hae.14457"],"URL":"https:\/\/doi.org\/10.1111\/hae.14457","archive":["Portico"],"relation":{},"ISSN":["1351-8216","1365-2516"],"issn-type":[{"value":"1351-8216","type":"print"},{"value":"1365-2516","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,20]]},"assertion":[{"value":"2021-09-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-29","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}