{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T04:07:25Z","timestamp":1748837245895,"version":"3.40.5"},"reference-count":40,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2022,1,30]],"date-time":"2022-01-30T00:00:00Z","timestamp":1643500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Haemophilic knee arthropathy presents functional and structural alterations and chronic pain. Self\u2010induced myofascial release aims to treat fascial restrictions and improve functionality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study investigated the safety and effectiveness of a self\u2010induced myofascial release protocol in patients with haemophilic knee arthropathy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Twenty\u2010five patients with bilateral haemophilic knee arthropathy were recruited (<jats:italic>n<\/jats:italic>\u00a0=\u00a050 knees). The patients followed an intervention protocol, with daily exercises for 8\u00a0weeks. The dependent variables were: safety of the technique (periodic telephone monitoring), joint state (Haemophilia Joint Health Score), pain intensity (visual analogue scale), pressure pain threshold (pressure dynamometer), range of motion (universal goniometer) and hamstring flexibility (Fingertip\u2010To\u2010Floor test). The resulting values were measured at baseline (T0) and after the intervention (T1). Paired t\u2010test compared the means between the assessments. Effect size was obtained using Cohen's d mean difference formula. The minimum detectable change of each variable was calculated.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were no cases of joint bleeding either during or after the procedure. The results showed improvements after the experimental period in joint state (Mean difference [MD]: 1.38; 95% confidence interval [95%CI]: .94;1.81), pain intensity (MD: 1.19; 95%CI: .70;1.67), pressure pain threshold (MD: \u201023.25; 95%CI: \u201026.25;\u201019.84), flexion (MD: \u20104.36; 95%CI: \u20105.70;\u20103.01), loss of extension (MD: 4.10; 95%CI: 3.01;5.18) and hamstring flexibility (MD: 3.54; 95%CI: 2.61;4.46).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Myofascial self\u2010release using a foam roller is safe in patients with haemophilic knee arthropathy. A myofascial self\u2010release protocol can improve perceived pain, range of motion and knee joint status, as well as hamstring flexibility in patients with haemophilic knee arthropathy.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hae.14498","type":"journal-article","created":{"date-parts":[[2022,1,31]],"date-time":"2022-01-31T04:28:53Z","timestamp":1643603333000},"page":"326-333","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Safety and efficacy of a self\u2010induced myofascial release protocol using a foam roller in patients with haemophilic knee arthropathy"],"prefix":"10.1111","volume":"28","author":[{"given":"Ra\u00fal","family":"P\u00e9rez\u2010Llanes","sequence":"first","affiliation":[{"name":"Department of Physical Therapy, Faculty of Health Sciences Catholic University of Murcia  Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elena","family":"Donoso\u2010\u00dabeda","sequence":"additional","affiliation":[{"name":"Department of Physical Therapy, Faculty of Health Sciences Catholic University of Murcia  Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Mero\u00f1o\u2010Gallut","sequence":"additional","affiliation":[{"name":"Physiotherapy Service, Tu Bienestar 360\u00b0 San Javier\u2010Murcia  Murcia Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Ucero\u2010Lozano","sequence":"additional","affiliation":[{"name":"Department of Physiotherapy European University of Madrid  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4276-6982","authenticated-orcid":false,"given":"Rub\u00e9n","family":"Cuesta\u2010Barriuso","sequence":"additional","affiliation":[{"name":"Department of Surgery and Medical\u2010Surgical Specialties, Faculty of Medicine University of Oviedo  Oviedo Spain"},{"name":"Royal Victoria Eugenia Foundation  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,1,30]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/hae.14046"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2010.03962.x"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminhematol.2008.03.017"},{"key":"e_1_2_8_5_1","unstructured":"GouwSC TimmerMA SrivastavaA et\u00a0al.Measurement of joint health in persons with haemophilia: A systematic review of the measurement properties of haemophilia\u2010specific instruments. 10."},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.21209"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsports-2018-099308"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbmt.2012.08.001"},{"key":"e_1_2_8_9_1","first-page":"174","article-title":"Fascia and tensegrity the quintessence of a unified systems conception","author":"Sharkey J","year":"2021","journal-title":"Int J Anat Appl Physiol"},{"volume-title":"Greenman's Principles of Manual Medicine","year":"2017","author":"DeStefano LA","key":"e_1_2_8_10_1"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1360-8592(02)00067-0"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1080\/09593985.2018.1425513"},{"issue":"1","key":"e_1_2_8_13_1","first-page":"41","article-title":"Safety and effectiveness of fascial therapy in adult patients with hemophilic arthropathy of ankle. 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