{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T09:48:44Z","timestamp":1751881724801,"version":"3.40.5"},"reference-count":27,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T00:00:00Z","timestamp":1659052800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>The Haemophilia Activities List (HAL) and paediatric HAL assess self\u2010reported limitations in various daily activities. To reduce patient burden, shorter versions of the pedHAL (22 items) and HAL (18 items) have been developed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Aim<\/jats:title><jats:p>This study aimed to determine the agreement between the pedHAL\/HAL<jats:sub>full<\/jats:sub> and pedHAL\/HAL<jats:sub>short<\/jats:sub> and construct validity and internal consistency of the pedHAL<jats:sub>\/<\/jats:sub>HAL<jats:sub>short<\/jats:sub> in persons with haemophilia (PWH).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A cross\u2010sectional secondary analysis of the Hemophilia in the Netherlands\u20106 national survey was performed. Adult and paediatric PWH completed the original pedHAL\/HAL<jats:sub>full<\/jats:sub>, from which pedHAL<jats:sub>\/<\/jats:sub>HAL<jats:sub>short<\/jats:sub> were derived. Score differences between the original and short versions were calculated. Construct validity was studied by testing hypotheses regarding the relationship of the pedHAL\/HAL<jats:sub>short<\/jats:sub> with the pedHAL\/HAL<jats:sub>full<\/jats:sub>, Haemophilia &amp; Exercise Project Test\u2010Questionnaire (HEP\u2010Test\u2010Q), Canadian Haemophilia Outcomes\u2010Kids\u2019 Life Assessment Tool (CHO\u2010KLAT) and RAND 36\u2010item Health Survey (RAND\u201036) (convergent\/discriminant validity) as well as its ability to discriminate between subgroups (known\u2010group validity). Internal consistency was assessed with Cronbach's <jats:italic>\u03b1<\/jats:italic>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We included 113 children (median 10y [range 4\u201317], 53% severe haemophilia) and 691 adults (median 51y [range 18\u201388], 35% severe). Scores of the pedHAL\/HAL<jats:sub>full<\/jats:sub> and pedHAL\/HAL<jats:sub>short<\/jats:sub> were similar with high correlations (&gt;0.9). Construct validity was confirmed for the pedHAL\/HAL<jats:sub>short<\/jats:sub>. The HAL<jats:sub>short<\/jats:sub> was able to discriminate between different disease severities and ages. Cronbach's <jats:italic>\u03b1<\/jats:italic> of the pedHAL\/HAL<jats:sub>short<\/jats:sub> was 0.95\u20130.97.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study confirmed the agreement between the pedHAL\/HAL<jats:sub>full<\/jats:sub> and the pedHAL\/HAL<jats:sub>short<\/jats:sub> and the construct validity of the pedHAL\/HAL<jats:sub>short<\/jats:sub>. The next step is to study construct validity of the pedHAL\/HAL<jats:sub>short<\/jats:sub> when administered as short forms.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hae.14628","type":"journal-article","created":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T18:14:20Z","timestamp":1659118460000},"page":"1007-1015","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Validation of the pedHAL<sub>short<\/sub> and HAL<sub>short<\/sub> in Dutch children and adults with haemophilia"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2920-2258","authenticated-orcid":false,"given":"Isolde A. R.","family":"Kuijlaars","sequence":"first","affiliation":[{"name":"Center for Benign Haematology Thrombosis and Haemostasis Van Creveldkliniek University Medical Center Utrecht Utrecht University  Utrecht the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2606-5104","authenticated-orcid":false,"given":"Janjaap","family":"van der Net","sequence":"additional","affiliation":[{"name":"Center for Child Development Exercise and Physical Literacy University Medical Center Utrecht Utrecht University University Children's Hospital  Utrecht the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3242-5524","authenticated-orcid":false,"given":"Lize F. D.","family":"van Vulpen","sequence":"additional","affiliation":[{"name":"Center for Benign Haematology Thrombosis and Haemostasis Van Creveldkliniek University Medical Center Utrecht Utrecht University  Utrecht the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariette H. E.","family":"Driessens","sequence":"additional","affiliation":[{"name":"Netherlands Haemophilia Society (NVHP)  Nijkerk the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saskia E. M.","family":"Schols","sequence":"additional","affiliation":[{"name":"Department of Haematology Radboud University Medical Center  Nijmegen the Netherlands"},{"name":"Haemophilia Treatment Center Nijmegen\u2010Eindhoven\u2010Maastricht Radboud University Medical Center  Nijmegen the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melanie","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Vascular Medicine Amsterdam Cardiovascular Sciences Amsterdam University Medical Centers University of Amsterdam  Amsterdam the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1957-4122","authenticated-orcid":false,"given":"Samantha C.","family":"Gouw","sequence":"additional","affiliation":[{"name":"Emma Children's Hospital Amsterdam UMC University of Amsterdam Pediatric Hematology  Amsterdam the Netherlands"},{"name":"Department of Clinical Epidemiology Leiden University Medical Center  Leiden the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7126-6613","authenticated-orcid":false,"given":"Kathelijn","family":"Fischer","sequence":"additional","affiliation":[{"name":"Center for Benign Haematology Thrombosis and Haemostasis Van Creveldkliniek University Medical Center Utrecht Utrecht University  Utrecht the 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