{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T18:37:32Z","timestamp":1767033452823},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T00:00:00Z","timestamp":1675296000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004326","name":"Bayer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004326","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008322","name":"CSL Behring","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004191","name":"Novo Nordisk","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004191","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004337","name":"Roche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004337","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012112","name":"Swedish Orphan Biovitrum","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012112","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>In the past decades, haemophilia treatment has greatly improved the health of persons with haemophilia (PWH). This study compares PWH to the general population on social conditions and health.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In December 2021, all Danes with moderate or severe haemophilia A or B, or von Willebrands disease type 3 were invited to participate in an online self\u2010report survey concerning sociodemographic factors, self\u2010rated health, teeth status, chronic health conditions, symptoms and loneliness. This study compares responses from the 124 adult male PWH with responses from a male general population sample (N\u00a0=\u00a04849). Analyses used logistic regression, controlling for age and highest completed education.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fewer PWH were in the oldest age group (65\u201084 years). Controlling for age, no significant differences were found regarding cohabitation status or education. Fewer PWH were employed (OR\u00a0=\u00a0.48, [.33\u2010.71])\u2014particularly in the 45\u201364 age group. PWH were less likely to report good health (OR\u00a0=\u00a0.49, [.31\u2010.77]). The odds of joint disease was much higher (OR\u00a0=\u00a013.00, [8.37\u201020.28]). Also, hypertension (OR\u00a0=\u00a02.25, [1.13\u20105.65]) and previous stroke (OR\u00a0=\u00a02.51, [1.44\u20103.50]) were more frequent. PWH were more likely to report pain in the arms\/hands\/legs\/hips (OR\u00a0=\u00a02.94, [1.92\u20104.52]), but less likely to report pain in the head\/neck\/shoulder (OR\u00a0=\u00a0.66, [.45\u2010.96]).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The disease burden of haemophilia has improved so PWH resembles the general population in areas such as marriage and education. However, even for young PWH, the disease still imposes a significant burden from hemophilia arthropathy and pain in extremities and joints. Middle\u2010aged PWH also have poorer levels of employment than same\u2010aged peers.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hae.14751","type":"journal-article","created":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T16:47:44Z","timestamp":1675356464000},"page":"538-544","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Health and quality of life of patients with haemophilia: A national study of 124 Danish men"],"prefix":"10.1111","volume":"29","author":[{"given":"Christina","family":"Schnohr","sequence":"first","affiliation":[{"name":"Department of Public Health University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ola","family":"Ekholm","sequence":"additional","affiliation":[{"name":"National Institute of Public Health  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lone Hvitfeldt","family":"Poulsen","sequence":"additional","affiliation":[{"name":"Centre for Haemophilia and Thrombosis Aarhus University  Aarhus Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lars","family":"Lehrmann","sequence":"additional","affiliation":[{"name":"The Danish Hemophilia Society  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Terkel","family":"Andersen","sequence":"additional","affiliation":[{"name":"The Danish Hemophilia Society  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eva","family":"Funding","sequence":"additional","affiliation":[{"name":"Department of Haematology Rigshospitalet  Copenhagen Denmark"},{"name":"Institute of Clinical Medicine University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen Binger","family":"Holm","sequence":"additional","affiliation":[{"name":"The Danish Hemophilia Society  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jakob Bue","family":"Bjorner","sequence":"additional","affiliation":[{"name":"Department of Public Health University of Copenhagen  Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,2,2]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pec.2007.06.006"},{"issue":"3","key":"e_1_2_8_3_1","first-page":"e66","article-title":"The relationship of self\u2010compassion and hope with quality of life for individuals with bleeding disorders","volume":"66","author":"Klein 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