{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T09:01:28Z","timestamp":1773046888840,"version":"3.50.1"},"reference-count":33,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,3,13]],"date-time":"2023-03-13T00:00:00Z","timestamp":1678665600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001602","name":"Science Foundation Ireland","doi-asserted-by":"publisher","award":["16\/SPP\/3303"],"award-info":[{"award-number":["16\/SPP\/3303"]}],"id":[{"id":"10.13039\/501100001602","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2023,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To conduct a cross\u2010sectional follow\u2010up assessment of physical activity (PA) in people with moderate and severe haemophilia (PwMSH) from the Irish Personalised Approach to the Treatment of Haemophilia (iPATH) study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Between June\u2013December 2021, participants\u2019 PA was measured over one week using accelerometery, and was compared with their previously measured data from the original iPATH assessment. Self\u2010awareness of PA and the impact of the Covid\u201019 pandemic on PA, pain, mobility and function were retrospectively examined using a survey.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Of 30 participants who returned surveys [<jats:italic>n<\/jats:italic>\u00a0=\u00a019, severe (FVIII, &lt;.01\u00a0IU\/mL); <jats:italic>n<\/jats:italic>\u00a0=\u00a04, moderate (FVIII, .01\u2013.05 IU\/mL); <jats:italic>n<\/jats:italic>\u00a0=\u00a07, severe (FIX, &lt;.01 IU\/mL); age: 47 (36, 55) years], 28 completed accelerometery (follow\u2010up time: 3 years). There were no significant differences in accelerometer PA (all <jats:italic>p<\/jats:italic>\u00a0&gt;\u00a0.05), but achievement of World Health Organisation guidelines increased (67.9%\u201375.0%; <jats:italic>p<\/jats:italic>\u00a0=\u00a0.646). Increased self\u2010awareness of PA was reported by 76.7%, and 66.7% reported desires to become more physically active. Compared to normal, most reported either no differences or lower levels of PA during lockdown restrictions. Self\u2010reported PA increased for most when restrictions eased from April 2021 onwards. Beyond the pandemic, concerns included pain and access to exercise resources.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Self\u2010reported PA throughout the pandemic was variable, whilst there were no significant differences in objectively measured PA between assessment periods, despite reports of increased self\u2010awareness and desires to be physically active at follow\u2010up. Further qualitative research is needed to design personalised PA and health interventions, capturing perspectives of patients, their families, and multi\u2010disciplinary haemophilia healthcare providers.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hae.14775","type":"journal-article","created":{"date-parts":[[2023,3,13]],"date-time":"2023-03-13T12:06:38Z","timestamp":1678709198000},"page":"892-899","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["A cross\u2010sectional follow\u2010up study of physical activity in adults with moderate and severe haemophilia"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9060-8022","authenticated-orcid":false,"given":"Megan","family":"Kennedy","sequence":"first","affiliation":[{"name":"Discipline of Physiotherapy, Trinity Centre for Health Sciences Trinity College Dublin, St. James's Hospital  Dublin 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Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9780-6972","authenticated-orcid":false,"given":"Brian","family":"O'Mahony","sequence":"additional","affiliation":[{"name":"Irish Haemophilia Society  Dublin Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2999-4216","authenticated-orcid":false,"given":"Michelle","family":"Lavin","sequence":"additional","affiliation":[{"name":"National Coagulation Centre St. James's Hospital  Dublin Ireland"},{"name":"Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Sciences Royal College of Surgeons in Ireland  Dublin Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James S.","family":"O'Donnell","sequence":"additional","affiliation":[{"name":"National Coagulation Centre St. James's Hospital  Dublin Ireland"},{"name":"Irish Centre for Vascular Biology, School of Pharmacy and Biomolecular Sciences Royal College of Surgeons in Ireland  Dublin Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter L.","family":"Turecek","sequence":"additional","affiliation":[{"name":"Baxalta Innovations GmbH A Member of the Takeda Group of Companies  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Gormley","sequence":"additional","affiliation":[{"name":"Discipline of Physiotherapy, Trinity Centre for Health Sciences Trinity College Dublin, St. James's Hospital  Dublin Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"the iPATH study 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