{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T18:40:02Z","timestamp":1789843202371,"version":"4.0.1"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2024,6,2]],"date-time":"2024-06-02T00:00:00Z","timestamp":1717286400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012112","name":"Swedish Orphan Biovitrum","doi-asserted-by":"publisher","award":["D10816"],"award-info":[{"award-number":["D10816"]}],"id":[{"id":"10.13039\/501100012112","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction\/aim<\/jats:title><jats:p>To evaluate whether patients with haemophilia (PwH) can be enabled to perform ultrasonography (US) of their knees without supervision according to the Haemophilia Early Arthropathy Detection with Ultrasound (HEAD\u2010US) protocol and whether they would be able to recognize pathologies.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Five PwH (mean age 29.6 years, range 20\u201348 years) were taught the use of a portable US device and the HEAD\u2010US protocol. Subsequently, the patients performed US unsupervised at home three times a week for a total of 6 weeks with a reteaching after 2 weeks. All images were checked for mapping of the landmarks defined in the HEAD\u2010US protocol by a radiologist. In a final test after the completion of the self\u2010sonography period, participants were asked to identify scanning plane and potential pathology from US images of other PwH.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>On the images of the self\u2010performed scans, 82.7% of the possible anatomic landmarks could be identified and 67.5% of the requested images were unobjectionable, depicting 100% of the required landmarks. There was a highly significant improvement in image quality following reteaching after 2 weeks (74.80\u00a0\u00b1\u00a036.88% vs. 88.31\u00a0\u00b1\u00a019.87%, <jats:italic>p<\/jats:italic>\u00a0&lt;\u00a0.001). In the final test, the participants identified the right scanning plane in 85.0% and they correctly identified pathology in 90.0% of images.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Appropriately trained PwH can perform the HEAD\u2010US protocol of their knee with high quality and are capable to identify pathologic findings on these standardized images. Asynchronous tele\u2010sonography could enable early therapy adjustment and thereby possibly reduce costs.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hae.15056","type":"journal-article","created":{"date-parts":[[2024,6,3]],"date-time":"2024-06-03T04:33:27Z","timestamp":1717389207000},"page":"1025-1031","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Self\u2010conducted sonographic monitoring of the knee in patients with haemophilia\u2014A feasibility study"],"prefix":"10.1111","volume":"30","author":[{"given":"Anna Christina","family":"Strauss","sequence":"first","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology University of Bonn  Bonn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natascha","family":"Marquardt","sequence":"additional","affiliation":[{"name":"Institute for Experimental Haematology and Transfusion Medicine University of Bonn  Bonn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1585-4100","authenticated-orcid":false,"given":"Johannes","family":"Oldenburg","sequence":"additional","affiliation":[{"name":"Institute for Experimental Haematology and Transfusion Medicine University of Bonn  Bonn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claus Christian","family":"Pieper","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology University of Bonn  Bonn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrike","family":"Attenberger","sequence":"additional","affiliation":[{"name":"Department of Diagnostic and Interventional Radiology University of Bonn  Bonn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0796-7831","authenticated-orcid":false,"given":"Jamil","family":"Hmida","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Trauma Surgery University of Bonn  Bonn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Rommelspacher","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Trauma Surgery University of Bonn  Bonn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Koob","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Trauma Surgery University of Bonn  Bonn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7777-3253","authenticated-orcid":false,"given":"Andreas Christian","family":"Strauss","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Trauma Surgery University of Bonn  Bonn Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,6,2]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.69B1.3546324"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2007.01625.x"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1160\/TH12-11-0874"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/hae.13429"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.4274\/tjh.galenos.2021.2020.0717"},{"issue":"6","key":"e_1_2_11_7_1","first-page":"S123","article-title":"Hemophilia in the managed care setting","volume":"21","author":"Dalton DR","year":"2015","journal-title":"Am J Manag 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