{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T03:57:22Z","timestamp":1781236642720,"version":"3.54.1"},"reference-count":40,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2025,4,20]],"date-time":"2025-04-20T00:00:00Z","timestamp":1745107200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,4,20]],"date-time":"2025-04-20T00:00:00Z","timestamp":1745107200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Haemophilia, an inherited bleeding disorder, impacts physical and mental health. With improving survival, the focus is on mental health issues.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>We examined and compared mental health issues in adolescents with haemophilia (AwH) in India with those of healthy controls. Additionally, we examined the relationship between quality of life and these mental health issues.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Standardized assessments were applied (between 2021 and 2022) on male cases (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a031) and controls (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a031) to measure psychiatric morbidity, psychosocial, and neuro\u2010cognitive functioning. Correlational analysis of quality of life with various mental health issues was also performed.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>AwH had more emotional, social and behavioural problems, poor quality of life, more cognitive dysfunction, with no statistically significant difference in self\u2010esteem as compared to healthy controls. There was a significant negative correlation between the quality of life and psychiatric morbidities, emotional and behavioural problems and cognitive dysfunction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>These findings corroborate evidence from other countries and emphasize the need for assessment of mental health issues and integration of mental health professionals in clinical services for AwH in India.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hae.70046","type":"journal-article","created":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T00:47:17Z","timestamp":1745196437000},"page":"874-883","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Study on Psychiatric Aspects, Psychosocial and Cognitive Functioning in Adolescents With Haemophilia"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-1485-3767","authenticated-orcid":false,"given":"Hemant","family":"Choudhary","sequence":"first","affiliation":[{"name":"Department of Psychiatry &amp; National Drug Dependence Treatment Centre (NDDTC) All India Institute of Medical Sciences (AIIMS)  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh","family":"Sagar","sequence":"additional","affiliation":[{"name":"Department of Psychiatry All India Institute of Medical Sciences (AIIMS)  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9760-7957","authenticated-orcid":false,"given":"Tulika","family":"Seth","sequence":"additional","affiliation":[{"name":"Department of Hematology All India Institute of Medical Sciences (AIIMS)  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachna","family":"Bhargava","sequence":"additional","affiliation":[{"name":"Department of Psychiatry &amp; National Drug Dependence Treatment Centre (NDDTC) All India Institute of Medical Sciences (AIIMS)  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bichitra Nanda","family":"Patra","sequence":"additional","affiliation":[{"name":"Department of Psychiatry All India Institute of Medical Sciences (AIIMS)  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,4,20]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"Report on the Annual Global Survey 2020","author":"World Federation of Hemophilia","year":"2021"},{"key":"e_1_2_9_3_1","volume-title":"Annual report 2019","author":"Garodia M.","year":"2019"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.18203\/2349-3291.ijcp20173196"},{"issue":"1","key":"e_1_2_9_5_1","first-page":"19","article-title":"Epidemiology & Social Costs of Haemophilia in India","volume":"140","author":"Kar A.","year":"2014","journal-title":"Indian Journal of Medical Research"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/pan.12255"},{"key":"e_1_2_9_7_1","first-page":"43","article-title":"Behavioral and Emotional Disturbances in Children With Hemophilia and Children With Acute Lymphoblastic Leukemia [ALL]","volume":"5","author":"Firoozi M.","year":"2019","journal-title":"Journal of Pediatric Nursing"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.32677\/IJCH.2017.v04.i04.011"},{"issue":"3","key":"e_1_2_9_9_1","first-page":"69","article-title":"Cognitive, Emotional, and Behavioral Problems of Children With Hemophilia","volume":"9","author":"Firoozi M.","year":"2017","journal-title":"Iranian Journal of Blood and Cancer"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/1756-185X.14352"},{"key":"e_1_2_9_11_1","first-page":"36","article-title":"Predictors of Caregiver's Burden: Interplay of Physical and Emotional Health and Perceived Hope in Children With Thalassemia and Hemophilia","volume":"11","author":"Muazzam A.","year":"2023","journal-title":"Pakistan Journal of Social and Clinical Psychology"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43054-020-00032-0"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2516.2003.00790.x"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2008.01971.x"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/hae.13960"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/hae.12010"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2516.2000.00416.x"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.28004"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(98)70151-9"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2011.02632.x"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.4103\/0975-2870.182501"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2012.02791.x"},{"issue":"3","key":"e_1_2_9_23_1","first-page":"e101","article-title":"Psychosocial Aspects of Haemophilia: A Systematic Review of Methodologies and Findings","volume":"18","author":"Cassis F.","year":"2011","journal-title":"Haemophilia"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.24287\/1726-1708-2020-19-3-12-16"},{"issue":"1","key":"e_1_2_9_25_1","first-page":"90","article-title":"Analysis of the Clinical Factors Affecting the Quality of Life in Children With Hemophilia A","volume":"3","author":"Wardhani A. 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