{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T19:27:15Z","timestamp":1783798035718,"version":"3.55.0"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T00:00:00Z","timestamp":1746403200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T00:00:00Z","timestamp":1746403200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Haemophilia"],"published-print":{"date-parts":[[2025,7]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background<\/jats:title>\n Haemophilia is a chronic, lifelong bleeding disorder that requires interdisciplinary care to manage and mitigate the disease burden throughout a patient's life. There is no universally accepted protocol for managing haemophilia patients during dental care.<\/jats:p>\n <\/jats:sec>\n \n Objective<\/jats:title>\n To evaluate the state of practice employed for people with haemophilia undergoing various dental treatment procedures under a comprehensive care model in a tertiary care setting.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Patient records from the archives of Haemophilia Society of Kasturba Hospital, Manipal were retrieved, and the demographic data, disease status and dental treatment records of each patient were systematically reviewed. The various dental procedures and the outcomes were correlated with the severity of haemophilia and the quantity of prophylactic factors concentrate utilised for the dental treatment procedures.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n A total of 73 patients attended the comprehensive Haemophilia clinic during the study period. Sixty nine of them underwent 84 dental treatment procedures. The various dental procedures that were performed on these patients were oral prophylaxis (scaling), extraction of grossly decayed teeth, restoration (fillings) of carious teeth, endodontic treatment and other minor oral surgical procedures. The amount of clotting factor concentrates given prior to dental treatment ranged from 250 to 1500 IU. None of the patients had excessive haemorrhage following dental procedures. Statistical analyses were performed with SPSS software, and statistical significance was set at\n p\u00a0<\u00a0<\/jats:italic>\n 0.05. Chi\u2010square and Fisher's exact test were used for the analysis of quantitative variables.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n Standardisation of prophylactic clotting factors for various dental treatment procedures is essential to prevent haemorrhagic complications.<\/jats:p>\n \n Trial Registration<\/jats:bold>\n : Clinical Trials Registry \u2010 India (CTRI) number: REF\/2024\/01\/077096\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/hae.70055","type":"journal-article","created":{"date-parts":[[2025,5,5]],"date-time":"2025-05-05T07:38:56Z","timestamp":1746430736000},"page":"617-624","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Outcomes of Dental Treatment Procedures in People With Haemophilia Treated Under a Comprehensive Care Model: An Analysis of Cases From a Tertiary Care Centre"],"prefix":"10.1111","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1245-2314","authenticated-orcid":false,"given":"Mathangi","family":"Kumar","sequence":"first","affiliation":[{"name":"Department of Oral Medicine & Radiology Manipal College of Dental Sciences, Manipal Manipal Academy of Higher Education Manipal Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2242-3413","authenticated-orcid":false,"given":"Sulochana","family":"Badagabettu","sequence":"additional","affiliation":[{"name":"Department of Fundamentals of Nursing Manipal College of Nursing Manipal Academy of Higher Education Manipal Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0967-5867","authenticated-orcid":false,"given":"Keerthilatha M.","family":"Pai","sequence":"additional","affiliation":[{"name":"Department of Dental Surgery Sikkim Manipal Institute of Medical Sciences Gangtok Sikkim India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4986-9893","authenticated-orcid":false,"given":"Annamma","family":"Kurien","sequence":"additional","affiliation":[{"name":"Manipal University College Malaysia Bukit Baru Melaka Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7616-6408","authenticated-orcid":false,"given":"Archana","family":"MV","sequence":"additional","affiliation":[{"name":"Department of Pediatric Hemato\u2010Oncology Kasturba Medical College and Hospital Manipal Academy of Higher Education Manipal Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0753-9490","authenticated-orcid":false,"given":"Shreemathi S.","family":"Mayya","sequence":"additional","affiliation":[{"name":"Department of Data Science Prasanna School of Public Health Manipal Academy of Higher Education Manipal Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2984-5053","authenticated-orcid":false,"given":"Sreejith","family":"Govindan","sequence":"additional","affiliation":[{"name":"Department\u00a0of Basic Medical Sciences Manipal Academy of Higher Education Manipal Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,5]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/107602960501100311"},{"issue":"4","key":"e_1_2_10_3_1","first-page":"253","article-title":"Hemophilia Treatment Center\u00a0: A Stratification Model for Developing Countries: A Pilot Study From India","volume":"4","author":"John M. 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