{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:51:40Z","timestamp":1787014300294,"version":"build-2736575974"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,5,29]],"date-time":"2013-05-29T00:00:00Z","timestamp":1369785600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hemodialysis International"],"published-print":{"date-parts":[[2014,1]]},"abstract":"Abstract<\/jats:title>\n \n Dialysis\u2010related amyloidosis (\n DRA<\/jats:styled-content>\n ) is a unique type of amyloidosis (beta\u20102 microglobulin) predominantly in end\u2010stage renal disease. Its clinical manifestations add to increased morbidity and reduced quality of life. There seems to be a relative risk reduction in\n DRA<\/jats:styled-content>\n manifestations when hemodialysis (\n HD<\/jats:styled-content>\n ) patients are treated with advanced\n HD<\/jats:styled-content>\n technology, but changes of the course of\n DRA<\/jats:styled-content>\n are uncertain. The aim of our investigation was to evaluate the prevalence and severity of carpal tunnel syndrome (\n CTS<\/jats:styled-content>\n ) in long\u2010term dialysis patients receiving either conventional or high\u2010flux, online\u2010produced ultrapure dialysis fluid. The cross\u2010sectional study included 147\n HD<\/jats:styled-content>\n patients (at least 10 years). The definitive diagnosis of\n CTS<\/jats:styled-content>\n was made histologically or by the coexistence of\n CTS<\/jats:styled-content>\n with other radiological\n DRA<\/jats:styled-content>\n manifestations (bone cysts, arthropathies). The two\n HD<\/jats:styled-content>\n patient groups did not differ significantly in age at start of\n HD<\/jats:styled-content>\n , gender, major co\u2010morbid diseases, anuria, and dialysis vintage. The conventional\n HD<\/jats:styled-content>\n group had significantly higher circulating beta\u20102 microglobulin and\n C<\/jats:styled-content>\n \u2010reactive protein (\n CRP<\/jats:styled-content>\n ) levels. The prevalence of\n DRA<\/jats:styled-content>\n was 68% for the conventional\n HD<\/jats:styled-content>\n group and 28% for the advanced\n HD<\/jats:styled-content>\n group. Duration of dialysis treatment was the only significant risk factor for the development of clinical\n DRA<\/jats:styled-content>\n manifestations in both study groups, but\n CTS<\/jats:styled-content>\n , bone cysts, or arthropathies occurred significantly earlier in conventional\n HD<\/jats:styled-content>\n patients. The prevalence and severity of\n DRA<\/jats:styled-content>\n have decreased with advances in dialysis technology during the last two decades, although its occurrence is simply delayed.\n <\/jats:p>","DOI":"10.1111\/hdi.12057","type":"journal-article","created":{"date-parts":[[2013,5,30]],"date-time":"2013-05-30T00:41:00Z","timestamp":1369874460000},"page":"136-141","source":"Crossref","is-referenced-by-count":28,"title":["Impact of advanced dialysis technology on the prevalence of dialysis\u2010related amyloidosis in long\u2010term maintenance dialysis patients"],"prefix":"10.1111","volume":"18","author":[{"given":"Helmut","family":"Schiffl","sequence":"first","affiliation":[{"name":"Department of Internal Medicine IV University Hospital Munich Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,5,29]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.arrt.2003.11.003"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1525-139X.2006.00134.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2009.03.655"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1997.262"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1992.207"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/13.suppl_7.61"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1159\/000169493"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.881937"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/039139889101401101"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/15.6.840"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1053\/ajkd.2001.27449"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000169048"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1991.128"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/31.3.157"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/5.6.432"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/039139880703001003"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1159\/000338923"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1997.431"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-4658.2011.08186.x"},{"key":"e_1_2_6_21_1","first-page":"368","article-title":"Comparative evaluation of beta 2\u2010microglobulin removal by different hemodialysis membranes: A six\u2010year follow\u2010up","volume":"63","author":"Mrowka C","year":"1993","journal-title":"Nephron"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(97)90281-X"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/17.10.1814"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-139x.2001.00031.x"},{"key":"e_1_2_6_25_1","first-page":"276","article-title":"Low\u2010molecular but not high\u2010molecular advanced glycation end products (AGEs) are removed by high\u2010flux dialysis","volume":"54","author":"Gerdemann A","year":"2000","journal-title":"Clin Nephrol"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.2001.4661"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/13.12.3118"}],"container-title":["Hemodialysis International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fhdi.12057","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hdi.12057","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T15:58:37Z","timestamp":1696348717000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hdi.12057"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5,29]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["10.1111\/hdi.12057"],"URL":"https:\/\/doi.org\/10.1111\/hdi.12057","archive":["Portico"],"relation":{},"ISSN":["1492-7535","1542-4758"],"issn-type":[{"value":"1492-7535","type":"print"},{"value":"1542-4758","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,5,29]]}}}