{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,4]],"date-time":"2023-10-04T05:41:47Z","timestamp":1696398107440},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2013,8,6]],"date-time":"2013-08-06T00:00:00Z","timestamp":1375747200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hemodialysis International"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Gross vascular calcification seen on imaging studies is common in hemodialysis (<jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content>) patients, and is a significant predictor for cardiovascular mortality in <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content> patients. We have reported that arterial microcalcification (<jats:styled-content style=\"fixed-case\">AMiC<\/jats:styled-content>) of the vascular access is associated with increased aortic stiffness. This study investigated the impact of vascular access <jats:styled-content style=\"fixed-case\">AMiC<\/jats:styled-content> on cardiovascular mortality in <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content> patients. The study included 149 <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content> patients (mean age: 59.1\u2009\u00b1\u200913.9 years, 86 men and 63 women, 65.8% diabetic) who underwent vascular access surgery. Radial or brachial artery specimens were obtained intraoperatively, and pathologic examination was performed using von <jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>ossa stain to identify <jats:styled-content style=\"fixed-case\">AMiC<\/jats:styled-content>. We compared all\u2010cause and cardiovascular mortality between patients with and without <jats:styled-content style=\"fixed-case\">AMiC<\/jats:styled-content>. The mean follow\u2010up was 37.8\u2009\u00b1\u200934.5 months, and <jats:styled-content style=\"fixed-case\">AMiC<\/jats:styled-content> was present in 38.8% (n\u2009=\u200957) of patients. The presence of diabetes (odds ratio: 16.49, 95% confidence interval: 1.81\u2013150.36, P\u2009=\u20090.013) was the only independent risk factor for vascular access <jats:styled-content style=\"fixed-case\">AMiC<\/jats:styled-content>. During the observational period, there were 27 cardiovascular deaths. <jats:styled-content style=\"fixed-case\">K<\/jats:styled-content>aplan\u2013<jats:styled-content style=\"fixed-case\">M<\/jats:styled-content>eier analysis showed an increased cardiovascular mortality risk (log rank\u2009=\u20094.83, P\u2009=\u20090.028) in <jats:styled-content style=\"fixed-case\">AMiC<\/jats:styled-content> patients, and <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ox regression analysis confirmed that <jats:styled-content style=\"fixed-case\">AMiC<\/jats:styled-content> was an independent predictor for cardiovascular mortality (hazard ratio: 2.35, 95% confidence interval: 1.09\u20135.09, P\u2009=\u20090.030). In conclusion, vascular access <jats:styled-content style=\"fixed-case\">AMiC<\/jats:styled-content> is a strong risk factor for cardiovascular mortality in <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content> patients.<\/jats:p>","DOI":"10.1111\/hdi.12074","type":"journal-article","created":{"date-parts":[[2013,8,6]],"date-time":"2013-08-06T11:13:46Z","timestamp":1375787626000},"page":"54-61","source":"Crossref","is-referenced-by-count":9,"title":["Impact of arterial microcalcification of the vascular access on cardiovascular mortality in hemodialysis patients"],"prefix":"10.1111","volume":"18","author":[{"given":"Yu Seon","family":"Yun","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Uijeongbu St. Mary's Hospital The Catholic University of Korea  Uijeongbu Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Su Jin","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Uijeongbu St. Mary's Hospital The Catholic University of Korea  Uijeongbu Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ja Young","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Uijeongbu St. Mary's Hospital The Catholic University of Korea  Uijeongbu Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Soo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Uijeongbu St. Mary's Hospital The Catholic University of Korea  Uijeongbu Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sun Ae","family":"Yoon","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Uijeongbu St. Mary's Hospital The Catholic University of Korea  Uijeongbu Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sun Chul","family":"Park","sequence":"additional","affiliation":[{"name":"Department of General Surgery Uijeongbu St. Mary's Hospital The Catholic University of Korea  Uijeongbu Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ok Ran","family":"Shin","sequence":"additional","affiliation":[{"name":"Department of Pathology Uijeongbu St. Mary's Hospital The Catholic University of Korea  Uijeongbu Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eun Joung","family":"Jang","sequence":"additional","affiliation":[{"name":"Department of Nursing Kyungbok University  Pocheon\u2010si Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Ok","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Uijeongbu St. Mary's Hospital The Catholic University of Korea  Uijeongbu 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