{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:13:53Z","timestamp":1759335233320},"reference-count":15,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2013,10,17]],"date-time":"2013-10-17T00:00:00Z","timestamp":1381968000000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hemodialysis International"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Calciphylaxis, also called calcific uremic arteriolopathy is a dreadful, life\u2010threatening ischemic vasculopathy, primarily involving skin and subcutaneous tissue, mostly on patients with end\u2010stage kidney disease. Calciphylaxis is a well\u2010described, but still a poorly understood disorder of mineral metabolism. Its occurrence is rare, but increasingly reported. We describe a 62\u2010year\u2010old obese lady on hemodialysis for end\u2010stage kidney disease due to type 2 diabetes, who developed two episodes of calciphylactic skin lesions during the 3 years observation. The healing of lesions in the first episode was prompted by a subtotal parathyroidectomy for severe secondary hyperparathyroidism. However, the resumption of oral calcium and vitamin <jats:styled-content style=\"fixed-case\">D<\/jats:styled-content> analog for the parathyroidectomy\u2010related hypocalcemia induced another occurrence of widespread calciphylactic skin lesions in areas of great adiposity. The typical regimen of <jats:styled-content style=\"fixed-case\">IV<\/jats:styled-content> sodium thiosulfate brought a successful outcome to the second episode. Now, growing numbers of successful treatment for calciphylaxis are reported with more specific therapies and a clear understanding of the pathogenetic mechanism is in sight.<\/jats:p>","DOI":"10.1111\/hdi.12087","type":"journal-article","created":{"date-parts":[[2013,10,17]],"date-time":"2013-10-17T15:13:09Z","timestamp":1382022789000},"source":"Crossref","is-referenced-by-count":12,"title":["Calciphylaxis and subtotal parathyroidectomy: A double\u2010edged sword"],"prefix":"10.1111","volume":"17","author":[{"given":"Madhavi","family":"Katikaneni","sequence":"first","affiliation":[{"name":"Nephrology Division Montefiore Medical Center \u2013 Wakefield Campus  Bronx New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Lwin","sequence":"additional","affiliation":[{"name":"Nephrology Division Montefiore Medical Center \u2013 Wakefield Campus  Bronx New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hugo","family":"Villanueva","sequence":"additional","affiliation":[{"name":"Nephrology Division Montefiore Medical Center \u2013 Wakefield Campus  Bronx New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinil","family":"Yoo","sequence":"additional","affiliation":[{"name":"Nephrology Division Montefiore Medical Center \u2013 Wakefield Campus  Bronx New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,10,17]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/MNH.0b013e32830f4566"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.134.3493.1876"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/ajkd.1998.v32.pm9740152"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2001.00803.x"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2002.00375.x"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfr658"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.08.065"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0190-9622(95)90286-4"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1067\/msy.2001.117101"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2004.03.018"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1159\/000332221"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1159\/000156486"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.06.029"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.12.006"},{"key":"e_1_2_5_16_1","first-page":"1004","volume-title":"Comprehensive Clinical Nephrology","author":"Evenepoel P","year":"2010"}],"container-title":["Hemodialysis International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fhdi.12087","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hdi.12087","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,11]],"date-time":"2023-09-11T21:31:35Z","timestamp":1694467895000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hdi.12087"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":15,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["10.1111\/hdi.12087"],"URL":"https:\/\/doi.org\/10.1111\/hdi.12087","archive":["Portico"],"relation":{},"ISSN":["1492-7535","1542-4758"],"issn-type":[{"value":"1492-7535","type":"print"},{"value":"1542-4758","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10]]}}}