{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T05:27:07Z","timestamp":1789018027313,"version":"build-2803163510"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,1,27]],"date-time":"2014-01-27T00:00:00Z","timestamp":1390780800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hemodialysis International"],"published-print":{"date-parts":[[2014,4]]},"abstract":"Abstract<\/jats:title>Frequent hemodialysis is associated with increased vascular access adverse events. We hypothesized that bacteremia would be more frequent in patients with central venous catheter (CVC<\/jats:styled-content>) than arteriovenous fistula or arteriovenous graft (AVF<\/jats:styled-content>\/AVG<\/jats:styled-content>) in nocturnal home hemodialysis (NHHD<\/jats:styled-content>). We reviewed blood culture reports and concurrent clinical data for a cohort of one hundred eighty\u2010seven NHHD<\/jats:styled-content> patients between J<\/jats:styled-content>anuary 1, 2006 and J<\/jats:styled-content>une 30, 2012. The primary outcome was time to first bacteremia, technique failure, or death after commencing NHHD<\/jats:styled-content>. Types of bacteremia and clinical consequences were analyzed. Analyses were adjusted for a priori defined confounders. One hundred eighty\u2010seven patients were included with a total follow up of six hundred five patient years. Initial vascular access was AVF<\/jats:styled-content> in seventy\u2010eight (42%) patients, AVG<\/jats:styled-content> in eleven (6%) patients, and CVC<\/jats:styled-content> in ninety\u2010eight (52%) patients. A total of 79.3% of patients with a CVC<\/jats:styled-content> reached the composite endpoint of bacteremia, technique failure, or death in the study period; 44.5% of patients with an AVF<\/jats:styled-content> or AVG<\/jats:styled-content> reached this composite endpoint. Adjusted time to first bacteremia, technique failure, or death was significantly shorter in patients with initial CVC<\/jats:styled-content> access (hazard ratio 2.42, 95% confidence interval 1.50\u20133.90, p\u2009<\u20090.001). Risk factors for bacteremia were comorbid status quantified by the Charlson Comorbidity Index (p\u2009<\u20090.001) and diabetes (p\u2009<\u20090.001). Coagulase negative staphylococcus was the commonest organism cultured accounting for 51.4% bacteremias. The second commonest organism was staphylococcus aureus (20.3% bacteremias). Patients undergoing NHHD<\/jats:styled-content> with a CVC<\/jats:styled-content> have a shorter duration to first infection, technique failure, or death than those with permanent vascular access.<\/jats:p>","DOI":"10.1111\/hdi.12140","type":"journal-article","created":{"date-parts":[[2014,1,28]],"date-time":"2014-01-28T02:07:52Z","timestamp":1390874872000},"page":"481-487","source":"Crossref","is-referenced-by-count":21,"title":["Vascular access\u2010related infection in nocturnal home hemodialysis"],"prefix":"10.1111","volume":"18","author":[{"given":"Wesley N.","family":"Hayes","sequence":"first","affiliation":[{"name":"Division of Nephrology Hospital for Sick Children Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karthik","family":"Tennankore","sequence":"additional","affiliation":[{"name":"Division of Nephrology Toronto General Hospital Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marisa","family":"Battistella","sequence":"additional","affiliation":[{"name":"Division of Nephrology Toronto General Hospital Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher T.","family":"Chan","sequence":"additional","affiliation":[{"name":"Division of Nephrology Toronto General Hospital Toronto Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,1,27]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.298.11.1291"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2011.213"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2012060595"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2012070643"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2013.03.028"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(87)90171-8"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(03)00415-3"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1542-4758.2010.00463.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5001744"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(03)00531-6"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2012121234"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.51.7111"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.11251210"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ASN.0000103870.31606.90"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2012.09.006"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfs378"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2369-12-28"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfp420"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/MAJ.0b013e3181637432"}],"container-title":["Hemodialysis International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fhdi.12140","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hdi.12140","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T13:16:47Z","timestamp":1696339007000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hdi.12140"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1,27]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["10.1111\/hdi.12140"],"URL":"https:\/\/doi.org\/10.1111\/hdi.12140","archive":["Portico"],"relation":{},"ISSN":["1492-7535","1542-4758"],"issn-type":[{"value":"1492-7535","type":"print"},{"value":"1542-4758","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,1,27]]}}}