{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T05:21:09Z","timestamp":1767676869511},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,1,27]],"date-time":"2014-01-27T00:00:00Z","timestamp":1390780800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hemodialysis International"],"published-print":{"date-parts":[[2014,7]]},"abstract":"Abstract<\/jats:title>Hemodialysis (HD<\/jats:styled-content>) patients have greater morbidity and mortality when they have a central venous catheter (CVC<\/jats:styled-content>) rather than an arteriovenous fistula (AVF<\/jats:styled-content>) access. Inflammation associated with dialysis catheter use and resultant higher C<\/jats:styled-content>\u2010reactive protein (CRP<\/jats:styled-content>) levels could have an independent adverse effect on patient outcomes. In this prospective study, we investigated whether HD<\/jats:styled-content> catheters induce inflammation independent of infection. We compared the mean levels of the inflammatory marker (CRP<\/jats:styled-content>) in 67 patients on maintenance HD<\/jats:styled-content> using noninfected catheters with 86 HD<\/jats:styled-content> patients using AVFs<\/jats:styled-content> at P<\/jats:styled-content>rince S<\/jats:styled-content>alman C<\/jats:styled-content>enter for K<\/jats:styled-content>idney D<\/jats:styled-content>iseases, S<\/jats:styled-content>audi A<\/jats:styled-content>rabia (KSA<\/jats:styled-content>), and J<\/jats:styled-content>ahra H<\/jats:styled-content>ospital, K<\/jats:styled-content>uwait, who met our inclusion criteria. C<\/jats:styled-content>\u2010reactive protein levels were measured every 2 months over a period of 6 months using immunoturbidimetric assay. One hundred fifty\u2010three patients on maintenance HD<\/jats:styled-content> for more than 6 months were included in the study, with mean age of 52.19\u2009\u00b1\u200916.06 years; 66% were males and 34% were females. Serial levels of mean CRP<\/jats:styled-content> were statistically and significantly higher in group with noninfected catheters (1.33, 1.24, and 1.10\u2009mg\/dL) compared to those with AVF<\/jats:styled-content>s (0.65, 0.59, and 0.68\u2009mg\/dL) with P<\/jats:styled-content> value of 0.000. In our study, we found no relation between CRP<\/jats:styled-content> level and age, sex, hemoglobin, albumin, calcium, phosphorus, and iPTH<\/jats:styled-content> level in both groups. Hemodialysis patients with a catheter have a heightened state of inflammation independent of infection, and thus our study supports the avoidance of catheters and a timely conversion to AVF<\/jats:styled-content>s with catheter removal.<\/jats:p>","DOI":"10.1111\/hdi.12145","type":"journal-article","created":{"date-parts":[[2014,1,28]],"date-time":"2014-01-28T02:08:40Z","timestamp":1390874920000},"page":"674-679","source":"Crossref","is-referenced-by-count":11,"title":["The level of C<\/scp>\u2010reactive protein in chronic hemodialysis patients: A comparative study between patients with noninfected catheters and arteriovenous fistula in two large G<\/scp>ulf hemodialysis centers"],"prefix":"10.1111","volume":"18","author":[{"given":"Alaa A.","family":"Sabry","sequence":"first","affiliation":[{"name":"Mansoura Urology and Nephrology Center Mansoura University Mansoura Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eid 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