{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,17]],"date-time":"2024-05-17T23:02:29Z","timestamp":1715986949384},"reference-count":18,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2014,3,16]],"date-time":"2014-03-16T00:00:00Z","timestamp":1394928000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hemodialysis International"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Myeloperoxidase is a proinflammatory protein that appears as a result of increased oxidative stress. It plays an important role in the promotion and progression of atherosclerosis. The aim of this study was to determine the importance of <jats:styled-content style=\"fixed-case\">MPO<\/jats:styled-content> as a predictive parameter for thrombosis of arteriovenous fistula (<jats:styled-content style=\"fixed-case\">AVF<\/jats:styled-content>). The study involved monitoring patients with <jats:styled-content style=\"fixed-case\">AVFs<\/jats:styled-content> for hemodialysis over a period of 2 years. There were 41 patients, 19 (46%) men and 22 (54%) women, with mean age of 65\u2009\u00b1\u200912.7 years. Routine laboratory analyses were carried out in all respondents, including determination of <jats:styled-content style=\"fixed-case\">MPO<\/jats:styled-content> concentration. Gender, demographic and anthropometrical characteristics, smoking, alcohol consumption, as well as the presence of diabetic nephropathy, as an etiological factor of kidney disease, were recorded. The group of patients who developed initial thrombosis of the <jats:styled-content style=\"fixed-case\">AVF<\/jats:styled-content>s had significantly different values for leukocytes (8.5\u2009\u00b1\u20093.8 vs. 7.3\u2009\u00b1\u20092.1, P\u2009=\u20090.024), erythrocytes (2.8\u2009\u00b1\u20090.27 vs. 3.2\u2009\u00b1\u20090.65; P\u2009=\u20090.019), hemoglobin (88.5\u2009\u00b1\u200981 vs. 99.1\u2009\u00b1\u20096.02; P\u2009=\u20090.041), and myeloperoxidase (19.3\u2009\u00b1\u20094.67 vs. 11.1\u2009\u00b1\u20094.43; P\u2009=\u20090.007) when compared with the group without fistula thrombosis. Diabetic nephropathy (P\u2009=\u20090.02) characterized the group of patients with thrombosis of the fistula. Diabetic nephropathy (B\u2009=\u20092.53, P\u2009=\u20090.049) and <jats:styled-content style=\"fixed-case\">MPO<\/jats:styled-content> (B\u2009=\u20090.03, P\u2009=\u20090.029) were statistically significant predictors of fistula thrombosis. In our study, <jats:styled-content style=\"fixed-case\">MPO<\/jats:styled-content> and diabetic nephropathy were predictors of thrombosis of the <jats:styled-content style=\"fixed-case\">AVF<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/hdi.12155","type":"journal-article","created":{"date-parts":[[2014,3,17]],"date-time":"2014-03-17T02:04:02Z","timestamp":1395021842000},"page":"680-685","source":"Crossref","is-referenced-by-count":2,"title":["Predictive value of serum myeloperoxidase activity for thrombosis of arteriovenous fistulas"],"prefix":"10.1111","volume":"18","author":[{"given":"Radojica V.","family":"Stolic","sequence":"first","affiliation":[{"name":"Internal Clinic Faculty of Medicine Pristina\/Kosovska Mitrovica University of Pristina  Kosovska Mitrovica Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Goran Z.","family":"Trajkovic","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Institute of Medical Statistics and Informatics University of Belgrade  Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirjana","family":"Kostic","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Pristina\/Kosovska Mitrovica Institute of Medical Statistics and Informatics University of Pristina  Kosovska Mitrovica Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dragica Z.","family":"Stolic","sequence":"additional","affiliation":[{"name":"Health Center Pristina, Gracanica  Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dijana J.","family":"Miric","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Pristina\/Kosovska Mitrovica Institute of Biochemistry University of Pristina  Kosovska Mitrovica Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bojana M.","family":"Kisic","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Pristina\/Kosovska Mitrovica Institute of Biochemistry University of Pristina  Kosovska Mitrovica Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Slavica D.","family":"Pajovic","sequence":"additional","affiliation":[{"name":"Internal Clinic Faculty of Medicine Pristina\/Kosovska Mitrovica University of Pristina  Kosovska Mitrovica Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladan M.","family":"Peric","sequence":"additional","affiliation":[{"name":"Internal Clinic Faculty of Medicine Pristina\/Kosovska Mitrovica University of Pristina  Kosovska Mitrovica 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