{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T05:48:00Z","timestamp":1695620880507},"reference-count":32,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2014,11,18]],"date-time":"2014-11-18T00:00:00Z","timestamp":1416268800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hemodialysis International"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report the outcome of a 52\u2010year\u2010old patient with diabetic nephropathy and receiving maintenance hemodialysis (<jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content>) using low molecular weight heparin (<jats:styled-content style=\"fixed-case\">LMWH<\/jats:styled-content>) as an anticoagulant for 2 years. He presented right lower limb pain accompanied with difficulty in walking for 2 months, and had no history of bleeding tendency or trauma. Physical examination revealed marked swelling and tenderness on his right lower limb. By ultrasound and magnetic resonance imaging (<jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>) diagnoses, the calf hematoma was diagnosed and identified with venous thrombosis. Following treatment with heparin\u2010free <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content>, the swelling regressed and pain subsided, and a follow\u2010up <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content> showed complete dissolution of hematoma. However, similar symptoms recurred in the right upper limb after 2 months without any predisposition, he was just placed on <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content> with <jats:styled-content style=\"fixed-case\">LMWH<\/jats:styled-content>, and symptoms regressed following the aforementioned therapy. This suggests that <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content> patients, especially with diabetic nephropathy having extremity hematoma, should be watched for the development of spontaneous hemorrhage that can be differentially diagnosed by imaging tests, such as <jats:styled-content style=\"fixed-case\">MRI<\/jats:styled-content>, and can be effectively treated with heparin\u2010free <jats:styled-content style=\"fixed-case\">HD<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/hdi.12246","type":"journal-article","created":{"date-parts":[[2014,11,18]],"date-time":"2014-11-18T08:23:08Z","timestamp":1416298988000},"source":"Crossref","is-referenced-by-count":2,"title":["Spontaneous calf hematoma in a patient with diabetic nephropathy receiving maintenance hemodialysis: A case report and review of the literature"],"prefix":"10.1111","volume":"19","author":[{"given":"Li","family":"Xiao","sequence":"first","affiliation":[{"name":"Department of Nephrology Central 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