{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T12:56:47Z","timestamp":1773665807895,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,2,4]],"date-time":"2015-02-04T00:00:00Z","timestamp":1423008000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hemodialysis International"],"published-print":{"date-parts":[[2015,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Although mushroom poisoning is a rare cause of acute renal injury, in some cases it may lead to the development of a severe and irreversible renal failure. Orellanus syndrome is the most important example of organic renal damage related to mushroom consumption. It is caused by the ingestion of orellanine, the main toxin of different types of <jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ortinarius mushrooms (<jats:styled-content style=\"fixed-case\"><jats:italic>C<\/jats:italic><\/jats:styled-content><jats:italic>ortinarius speciosissimus<\/jats:italic>, <jats:styled-content style=\"fixed-case\"><jats:italic>C<\/jats:italic><\/jats:styled-content><jats:italic>.\u2009orellanus<\/jats:italic>, <jats:styled-content style=\"fixed-case\"><jats:italic>C<\/jats:italic><\/jats:styled-content><jats:italic>.\u2009orellanoides<\/jats:italic>, etc.), and it is characterized by progressive clinical phases with a predominant kidney involvement, finally requiring renal replacement therapy in about 10% of cases. Renal damage is often late and associated with a histological picture of interstitial nephritis. Diagnosis is essentially clinical and no specific therapy has been shown to be effective in preventing and treating renal damage. Here, we describe the case of a patient with mixed wild mushroom poisoning, presenting the typical clinical signs and course of the <jats:styled-content style=\"fixed-case\">O<\/jats:styled-content>rellanus syndrome. This case offers us the opportunity to review the main clinical features of this severe and little\u2010known intoxication.<\/jats:p>","DOI":"10.1111\/hdi.12275","type":"journal-article","created":{"date-parts":[[2015,2,4]],"date-time":"2015-02-04T06:08:46Z","timestamp":1423030126000},"source":"Crossref","is-referenced-by-count":10,"title":["Renal involvement in mushroom poisoning: The case of <scp>O<\/scp>rellanus syndrome"],"prefix":"10.1111","volume":"19","author":[{"given":"Pasquale","family":"Esposito","sequence":"first","affiliation":[{"name":"Department of Nephrology, Dialysis and Transplantation Fondazione IRCCS Policlinico San Matteo University of Pavia  Pavia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edoardo","family":"La Porta","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Dialysis and Transplantation Fondazione IRCCS Policlinico San Matteo University of Pavia  Pavia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Calatroni","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Dialysis and Transplantation Fondazione IRCCS Policlinico San Matteo University of Pavia  Pavia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefania","family":"Bianzina","sequence":"additional","affiliation":[{"name":"First Department of Anesthesia and Intensive Care Fondazione IRCCS Policlinico San Matteo University of Pavia  Pavia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmelo","family":"Libetta","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Dialysis and Transplantation Fondazione IRCCS Policlinico San Matteo University of Pavia  Pavia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marilena","family":"Gregorini","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Dialysis and Transplantation Fondazione IRCCS Policlinico San Matteo University of Pavia  Pavia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa","family":"Rampino","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Dialysis and Transplantation Fondazione IRCCS Policlinico San Matteo University of Pavia  Pavia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Dal Canton","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Dialysis and Transplantation Fondazione IRCCS Policlinico San Matteo University of Pavia  Pavia Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,2,4]]},"reference":[{"key":"e_1_2_4_2_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.00360114"},{"key":"e_1_2_4_3_1","doi-asserted-by":"publisher","DOI":"10.1517\/14740330903311023"},{"key":"e_1_2_4_4_1","first-page":"17","article-title":"Ethylene glycol and methanol poisonings: Case series and review","volume":"106","author":"Montjoy CA","year":"2010","journal-title":"W V Med J"},{"key":"e_1_2_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(80)92104-2"},{"key":"e_1_2_4_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/096032718400300406"},{"key":"e_1_2_4_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-0101(00)00248-8"},{"key":"e_1_2_4_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-010-1545-7"},{"key":"e_1_2_4_9_1","doi-asserted-by":"publisher","DOI":"10.5414\/CNP71557"},{"key":"e_1_2_4_10_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1444-0903.2001.00199.x"},{"key":"e_1_2_4_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0300-483X(91)90163-U"},{"key":"e_1_2_4_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2008.01.017"},{"key":"e_1_2_4_13_1","doi-asserted-by":"publisher","DOI":"10.3109\/10715769809097875"},{"key":"e_1_2_4_14_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2559.1997.d01-597.x"},{"key":"e_1_2_4_15_1","doi-asserted-by":"publisher","DOI":"10.3109\/15563659709001167"},{"key":"e_1_2_4_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfr511"},{"key":"e_1_2_4_17_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2003.12.037"},{"key":"e_1_2_4_18_1","first-page":"58","article-title":"Efficiency of haemoperfusion materials at removing the fungal toxin orellanine from human plasma","volume":"53","author":"Fulde K","year":"1998","journal-title":"Pharmazie"},{"key":"e_1_2_4_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/14.11.2779-a"},{"key":"e_1_2_4_20_1","first-page":"1920","article-title":"Renal transplantation after Cortinarius speciosissimus poisoning","volume":"10","author":"Holmdahl J","year":"1995","journal-title":"Nephrol Dial Transplant"},{"key":"e_1_2_4_21_1","article-title":"Successful living related kidney transplantation for end\u2010stage renal failure caused by Orellanine syndrome","author":"Nagaraja P","year":"2012","journal-title":"QJM"}],"container-title":["Hemodialysis International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fhdi.12275","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hdi.12275","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T15:34:58Z","timestamp":1695569698000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hdi.12275"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,4]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,10]]}},"alternative-id":["10.1111\/hdi.12275"],"URL":"https:\/\/doi.org\/10.1111\/hdi.12275","archive":["Portico"],"relation":{},"ISSN":["1492-7535","1542-4758"],"issn-type":[{"value":"1492-7535","type":"print"},{"value":"1542-4758","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2,4]]}}}