{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T07:11:25Z","timestamp":1695971485569},"reference-count":21,"publisher":"Wiley","issue":"S2","license":[{"start":{"date-parts":[[2017,10,24]],"date-time":"2017-10-24T00:00:00Z","timestamp":1508803200000},"content-version":"vor","delay-in-days":23,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Hemodialysis International"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label \/><jats:p><jats:bold>Introduction:<\/jats:bold> We first described the syndrome of rapid onset end stage renal disease (SORO\u2010ESRD), acute yet irreversible renal failure, in 2010.<\/jats:p><jats:p><jats:bold>Objective:<\/jats:bold> The impact of SORO\u2010ESRD renal allograft survival remains speculative and we plan to study this question.<\/jats:p><jats:p><jats:bold>Methods:<\/jats:bold> A retrospective analysis of individual adult patient\u2010level serum creatinine trajectories of ESRD patients on maintenance hemodialysis for &gt;90 days at Mayo Clinic, Rochester, 2001\u20132013.<\/jats:p><jats:p><jats:bold>Results:<\/jats:bold> Of 1461 ESRD patients, 149 (10%) patients including 13 renal transplant recipients (RTRs) satisfied the diagnosis of SORO\u2010ESRD \u2010 4 males, 9 females, 12 Caucasians\/one other, age 45 (18\u201383) years. Serum creatinine was 1.4 (0.8\u20131.7) mg\/dL in the last year before hemodialysis initiation. Initial hemodialysis access was a dialysis catheter in all 13 patients. AKI precipitating SORO\u2010ESRD followed acute rejection (4), postoperative (2), tubulo\u2010interstitial nephritis (2), unknown (2), infection\/sepsis (1), contrast nephropathy (1), BKV nephropathy (1), and cardio\u2010renal syndrome (1). Renal allograft survival was 1469 (277\u20134939) days (4 years). Renal allograft biopsies were available in 9\/14 (69%) RTRs \u2010 Four showed acute rejection, two of which followed interruption of immunosuppression, three revealed acute tubular necrosis and four others also showed chronic transplant glomerulopathy. Time on hemodialysis was 856 (129\u20131630) days (2.4 years). 5\/13 RTRs with SORO\u2010ESRD (38%) died \u2010 3 (60%) following cardiac arrest, 2 (40%) after stopping hemodialysis. 4\/13 (31%) were re\u2010transplanted in the period of this study.<\/jats:p><jats:p><jats:bold>Conclusion:<\/jats:bold> SORO\u2010ESRD contributed significantly to late renal allograft loss and return to hemodialysis with 100% initial dialysis catheter rate. Potentially preventable causes of AKI leading to SORO\u2010ESRD were identified. The application of experience gained from such studies would help reduce late renal allograft loss and the need for re\u2010transplantation. This would further help reduce the yawning gap between need and availability of donor kidney organs both here in the United States and around the world. Larger studies are warranted.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hdi.12597","type":"journal-article","created":{"date-parts":[[2017,10,24]],"date-time":"2017-10-24T11:30:15Z","timestamp":1508844615000},"source":"Crossref","is-referenced-by-count":0,"title":["A Mayo Clinic 13\u2010year investigation of the syndrome of rapid onset ESRD among renal transplant recipients: An analysis of the implications of renal allograft biopsy results"],"prefix":"10.1111","volume":"21","author":[{"given":"Macaulay Amechi","family":"Onuigbo","sequence":"first","affiliation":[{"name":"Mayo Clinic College of Medicine Rochester Minnesota USA"},{"name":"Department of Nephrology Mayo Clinic Health System Eau Claire Wisconsin USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nneoma","family":"Agbasi","sequence":"additional","affiliation":[{"name":"North East London NHS Foundation Trust Ilford Essex, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,10,24]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.3109\/0886022X.2010.502608"},{"key":"e_1_2_6_3_1","first-page":"443","volume-title":"Hemodialysis: How, When and Why","author":"Onuigbo MAC","year":"2012"},{"key":"e_1_2_6_4_1","volume-title":"Chronic Kidney Disease and RAAS Blockade: A New View of Renoprotection","author":"Onuigbo MA","year":"2011"},{"key":"e_1_2_6_5_1","first-page":"109","volume-title":"ACE Inhibitors: Medical Uses, Mechanisms of Action, Potential Adverse Effects and Related Topics","author":"Onuigbo MA","year":"2013"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/0971-4065.111861"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.4103\/0971-4065.127886"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/0886022X.2015.1088336"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)11445-8"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2007040422"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1159\/000145453"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.47.1171"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfn772"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2369-12-5"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2011.11.044"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.110895"},{"key":"e_1_2_6_17_1","article-title":"Increasing trends in acute dialysis after elective surgery, 1995\u20102009: how often does AKI directly lead to irreversible ESRD all in one fell swoop?","author":"Onuigbo MA.","journal-title":"CMAJ."},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2011.11.034"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transproceed.2015.04.077"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.14099"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000001326"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2015.2430"}],"container-title":["Hemodialysis International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fhdi.12597","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hdi.12597","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,28]],"date-time":"2023-09-28T20:04:30Z","timestamp":1695931470000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hdi.12597"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":21,"journal-issue":{"issue":"S2","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["10.1111\/hdi.12597"],"URL":"https:\/\/doi.org\/10.1111\/hdi.12597","archive":["Portico"],"relation":{},"ISSN":["1492-7535","1542-4758"],"issn-type":[{"value":"1492-7535","type":"print"},{"value":"1542-4758","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10]]}}}