{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,4]],"date-time":"2023-09-04T08:53:19Z","timestamp":1693817599602},"reference-count":19,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2020,6,14]],"date-time":"2020-06-14T00:00:00Z","timestamp":1592092800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Hemodialysis International"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>This study aimed to determine whether predialysis blood gases is affected by altitude differences in hemodialysis patients with arteriovenous fistulas living in Turkey at three different altitudes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients' predialysis blood gases were compared by standardizing both arterial blood gases collections and working methods for patients undergoing hemodialysis using a dialysate with the same properties at altitudes of 30\u2009m (sea level), 1020\u2009m (moderate altitude), and 1951\u2009m (high altitude).<\/jats:p><\/jats:sec><jats:sec><jats:title>Findings<\/jats:title><jats:p>Blood gases disorders were detected in 32 (82.1%) high altitude group patients, whereas 49 (74.2%) sea level group patients had no blood gases disorders (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). pH values in the high altitude group were significantly lower than those in the other groups, and the pH increased as altitude decreased (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). The partial pressure of carbon dioxide (PaCO<jats:sub>2<\/jats:sub>) values was higher in the sea level group than in the other groups and increased at lower sea levels (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). Bicarbonate values were significantly higher in the sea level group than in the other groups and increased at lower sea levels, similar to PaCO<jats:sub>2<\/jats:sub> values (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). The partial pressure of oxygen (PaO<jats:sub>2<\/jats:sub>) values in the high altitude and sea level groups were significantly higher and increased at lower sea levels (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001). The oxygen saturation (SaO<jats:sub>2<\/jats:sub>) values were significantly lower in the high altitude group than in the other groups and increased gradually at lower sea levels (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Discussion<\/jats:title><jats:p>Predialysis metabolic acidosis was more pronounced in patients undergoing hemodialysis at high altitudes, whereas PaCO<jats:sub>2<\/jats:sub>, PaO<jats:sub>2<\/jats:sub>, and SaO<jats:sub>2<\/jats:sub> values were lower.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hdi.12844","type":"journal-article","created":{"date-parts":[[2020,6,15]],"date-time":"2020-06-15T03:45:04Z","timestamp":1592192704000},"page":"323-329","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Does altitude affect blood gases in hemodialysis patients?"],"prefix":"10.1111","volume":"24","author":[{"given":"Yasemin","family":"Co\u015fkun Yavuz","sequence":"first","affiliation":[{"name":"Nephrology Department Faculty of Medicine, Selcuk University  Konya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eda","family":"Altun","sequence":"additional","affiliation":[{"name":"Nephrology Depatment Golcuk Necati Celik State Hospital  Kocaeli Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Can","family":"Sevinc","sequence":"additional","affiliation":[{"name":"Nephrology Department Faculty of Medicine, Ataturk University  Erzurum Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibrahim","family":"Guney","sequence":"additional","affiliation":[{"name":"Nephrology Department Konya Training and Research Hospital, Health Sciences University  Konya Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muslu Kazim","family":"Korez","sequence":"additional","affiliation":[{"name":"Statistics Department Faculty of Science, Selcuk University  Konya 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