{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T06:17:10Z","timestamp":1768630630528,"version":"3.49.0"},"reference-count":12,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T00:00:00Z","timestamp":1639440000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Hemodialysis International"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Severe metabolic alkalosis is rarely seen in end stage renal disease (ESRD) patients on long\u2010term hemodialysis. This can be life threatening and mortality is exponentially increased when the pH exceeds 7.60. Persistent vomiting, ingestion of alkali for dyspepsia and pica behavior are all potential causes of such severe metabolic alkalosis. The prevalence of pica is increased in chronic kidney disease and ESRD patients, with ice being the most commonly ingested substance. It can cause a myriad of complications including death, but the diagnosis may be elusive unless the pica behavior is witnessed firsthand by others since patients do not typically disclose their behavior. We present the case of a hemodialysis patient with severe alkalemia, hypernatremia, and excessive interdialytic weight gains resulting in recurrent hospitalizations for fluid overload due to baking soda pica behavior.<\/jats:p>","DOI":"10.1111\/hdi.12984","type":"journal-article","created":{"date-parts":[[2021,12,15]],"date-time":"2021-12-15T04:39:15Z","timestamp":1639543155000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Life\u2010threatening alkalosis from baking soda pica in an end stage renal disease hemodialysis patient"],"prefix":"10.1111","volume":"26","author":[{"given":"Amara","family":"Sarwal","sequence":"first","affiliation":[{"name":"Division of Nephrology University of Utah  Salt Lake City Utah USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Kim","sequence":"additional","affiliation":[{"name":"Division of Nephrology Lincoln Medical Center, New York City Health and Hospitals  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isaiarasi","family":"Gnanasekaran","sequence":"additional","affiliation":[{"name":"Division of Nephrology Lincoln Medical Center, New York City Health and Hospitals  New York New York USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,12,14]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007611-198706000-00016"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000170004"},{"issue":"4","key":"e_1_2_6_4_1","first-page":"280","article-title":"Baking soda induced severe metabolic alkalosis in a haemodialysis patient","volume":"2","author":"Solak Y","year":"2009","journal-title":"NDT"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1159\/000045101"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.5414\/CNP66071"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/14.2.452"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0736-4679(98)00123-1"},{"issue":"2","key":"e_1_2_6_9_1","first-page":"111","article-title":"Pica in end\u2010stage chronic kidney disease: literature review","volume":"39","author":"Orozco\u2010Gonz\u00e1lez CN","year":"2019","journal-title":"Nefrologia"},{"issue":"5","key":"e_1_2_6_10_1","first-page":"66","article-title":"The incidence of pica in a sample of dialysis patients","volume":"1","author":"Stillman MA","year":"2009","journal-title":"J Psychol Counsel"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1051-2276(99)90017-1"},{"key":"e_1_2_6_12_1","first-page":"232A","article-title":"Pica: an important and unrecognized problem in the treatment of ESRD patients on chronic dialysis","volume":"10","author":"Abitbol C","year":"1999","journal-title":"J Am Soc Nephrol"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jrn.2018.08.002"}],"container-title":["Hemodialysis International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hdi.12984","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/hdi.12984","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hdi.12984","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T12:15:56Z","timestamp":1692965756000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hdi.12984"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,14]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["10.1111\/hdi.12984"],"URL":"https:\/\/doi.org\/10.1111\/hdi.12984","archive":["Portico"],"relation":{},"ISSN":["1492-7535","1542-4758"],"issn-type":[{"value":"1492-7535","type":"print"},{"value":"1542-4758","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,14]]},"assertion":[{"value":"2021-07-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-30","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-14","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}