{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,3,28]],"date-time":"2024-03-28T18:02:01Z","timestamp":1711648921025},"reference-count":36,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T00:00:00Z","timestamp":1680480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Hemodialysis International"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Arteriovenous fistula (AVF) is a primary dialysis vascular access commonly used for maintaining hemodialysis (MHD) patients. Vitamin D (VD) is a fat\u2010soluble steroid hormone that is closely related to vascular endothelial function. This study aimed to investigate the association between VD metabolites and AVF failure in patients undergoing HD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This study included 443 HD patients using AVF between January 2010 and January 2020. The AVF operations in these patients were newly created by the same physician. We analyzed the AVF patency rates using the chi\u2010square test. Univariate and multivariate logistic regression analyses were performed to explore risk factors for AVF failure. Survival analysis was performed to explore AVF survival at different serum 25\u2010hydroxyvitamin D (25(OH)D) concentrations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Logistic regression analyses showed that male sex; age; BMI; serum albumin, triglyceride, phosphorus, 25(OH)D, iPTH and hemoglobin levels, history of hypertension, CHD, diabetes, stroke, and antiplatelet drug use; and smoking habits were not risk factors for AVF failure. The failure incidence rates of AVF in subjects in the VD deficiency and non VD deficiency group were not statistically significant (25.0% vs. 30.8%, <jats:italic>p<\/jats:italic>\u00a0=\u00a00.344). The AVF failure incidence rates at 1, 3, and 5\u2009years in the patients with 25(OH)D levels more than 20\u2009ng\/mL were 26%, 29%, and 37%, respectively, and the one\u2010year AVF failure incidence rates were 27% in the patients with 25(OH)D levels less than 20\u2009ng\/mL. In addition, the Kaplan\u2013Meier analysis suggested that the no significant differences were noted when calculating the cumulative survival rates of AVF between the two groups within 50\u2009months of AVF using.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Our findings suggest that 25(OH)D deficiency is not associated with AVF failure incidence rates, and that 25(OH)D deficiency has no significant impact on long\u2010term cumulative AVF survival rate.<\/jats:p><\/jats:sec>","DOI":"10.1111\/hdi.13080","type":"journal-article","created":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T12:35:54Z","timestamp":1680525354000},"page":"231-240","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Association of vitamin D metabolites with arteriovenous fistula function in hemodialysis patients: A single center study"],"prefix":"10.1111","volume":"27","author":[{"given":"Hong","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Nephrology The Third Xiangya Hospital of Central South University  Changsha Hunan Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Na","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Nephrology The Third Xiangya Hospital of Central South University  Changsha Hunan Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ai\u2010mei","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Nephrology The Third Xiangya Hospital of Central South University  Changsha Hunan Province China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qin","family":"Dai","sequence":"additional","affiliation":[{"name":"Department of Nephrology The Third Xiangya Hospital of Central South University  Changsha Hunan Province 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