{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:51:53Z","timestamp":1787014313586,"version":"build-2736575974"},"reference-count":32,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Hemodialysis International"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The prevalence rates of hepatosteatosis and gallstones are increasing owing to the multifactorial causes of chronic kidney disease, and the prevalence may change with the availability of different forms of renal replacement therapy. We aimed to determine the incidence or prevalence rates of hepatosteatosis, cholelithiasis, and acute cholecystitis in patients with chronic kidney disease and compare them between renal replacement therapy modalities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 270 patients (90 with chronic kidney disease stages III\u2013V, 90 undergoing peritoneal dialysis, and 90 undergoing hemodialysis) were included and categorized into the pre\u2010dialysis, hemodialysis, and peritoneal dialysis groups. The patients were questioned about previous gallbladder surgeries and chronic diseases. The results of abdominal ultrasonography, tomography, and magnetic resonance imaging were retrospectively evaluated with respect to the findings on the hepatobiliary system. Hepatosteatosis and cholelithiasis were diagnosed by expert radiologists on the basis of abdominal ultrasonography, tomography, and magnetic resonance imaging findings. The prevalence rates of hepatosteatosis, cholelithiasis, and other liver findings were compared between the groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>\n                      Hepatosteatosis and cholelithiasis were detected in 16.7% and 21.5% of the 270 cases, respectively. Hepatosteatosis was present in 17.8%, 25.6%, and 6.7% of patients in the pre\u2010dialysis, hemodialysis, and peritoneal dialysis groups, respectively. The prevalence of hepatosteatosis was significantly higher in patients undergoing hemodialysis than in patients undergoing peritoneal dialysis (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.002). However, no statistically significant difference was found between the peritoneal dialysis and pre\u2010dialysis groups or between the hemodialysis and pre\u2010dialysis groups (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;0.05). The prevalence rates of cholelithiasis were 15.6%, 28.9%, and 20.0%, in the pre\u2010dialysis, hemodialysis, and peritoneal dialysis groups, respectively, and there were no statistically significant differences among the groups. The incidence of acute cholecystitis was significantly higher in the hemodialysis group than in the pre\u2010dialysis group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Our study showed that the hepatobiliary system is frequently affected in chronic kidney disease and that the findings may differ depending on the renal replacement therapy modality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hdi.13151","type":"journal-article","created":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T03:54:17Z","timestamp":1711943657000},"page":"343-350","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Evaluation of hepatosteatosis and gallstone disease in patients with chronic kidney disease"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5387-2000","authenticated-orcid":false,"given":"Do\u011fu","family":"Karahan","sequence":"first","affiliation":[{"name":"Department of Internal Medicine Malatya Turgut \u00d6zal University School of Medicine  Malatya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8683-3737","authenticated-orcid":false,"given":"\u0130dris","family":"\u015eahin","sequence":"additional","affiliation":[{"name":"Department of Nephrology \u0130nonu University School of Medicine  Malatya Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01321.x"},{"key":"e_1_2_8_3_1","unstructured":"\u015eahin\u0130.Kronik b\u00f6brek yetmezli\u011finde \u00e7\u00f6lyak hastal\u0131\u011f\u0131 prevelans\u0131 ve \u00e7\u00f6lyak hastal\u0131\u011f\u0131 saptanan olgularda \u00e7\u00f6lyak hastal\u0131\u011f\u0131n\u0131n beslenme parametreleri anemi ve sekonder hiperparatiroidi \u00fczerine etkileri. Yan dal uzmanl\u0131k tezi. Y\u00fcz\u00fcnc\u00fc Y\u0131l \u00dcniversitesi T\u0131p Fak\u00fcltesi \u0130\u00e7 Hastal\u0131klar\u0131 Anabilim Dal\u0131 Nefroloji Bilim Dal\u0131. Tez Y\u00fcr\u00fct\u00fcc\u00fcs\u00fc: Do\u00e7.Dr. Reha Erko\u00e7 Van.2004."},{"key":"e_1_2_8_4_1","first-page":"139","article-title":"Prevalence of cholelithiasis in a Turkish population of end\u2010stage renal failure patients and related risk factors: experience of a center from Turkey","volume":"19","author":"Erten S","year":"2008","journal-title":"Turk J Gastroenterol"},{"issue":"3","key":"e_1_2_8_5_1","first-page":"289","article-title":"Cholelithiasis: presentation and management","volume":"64","author":"Littlefield A","year":"2019","journal-title":"J MidwiferyWomen's Health"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10140-021-01999-y"},{"issue":"1","key":"e_1_2_8_7_1","first-page":"21","article-title":"Are dialysis\u2010patients a risk population for cholelithiasis? Study in an apulian population","volume":"61","author":"Gernone G","year":"2009","journal-title":"Minerva Urol Nefrol"},{"key":"e_1_2_8_8_1","article-title":"Nonalcoholic fatty liver disease\u2010related chronic kidney disease","volume":"29","author":"Cojocariu C","year":"2020","journal-title":"Can J Gastroenterol Hepatol"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/joim.12964"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2020.154170"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0033-1334866"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2002.05772.x"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/8490242"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sult.2021.03.001"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lpm.2011.01.024"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1055\/a-1401-2170"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/00129689-200410000-00003"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12944-019-1184-3"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/08860220500234949"},{"key":"e_1_2_8_20_1","first-page":"1792","article-title":"Prevalence of gallstone disease in patients with end\u2010stage renal disease treated with hemodialysis in Korea","volume":"50","author":"Hahm JS","year":"2003","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2003.07382.x"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.5152\/tjg.2014.4854"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rgmx.2012.11.002"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1080\/0886022X.2017.1419971"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/08860220701260636"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2012.08.022"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.23876\/j.krcp.20.250"},{"key":"e_1_2_8_28_1","first-page":"176","article-title":"Diyabet ve karaci\u011fer ya\u011flanmas\u0131","volume":"26","author":"Satman \u0130","year":"2006","journal-title":"T\u00fcrkiye Klinikleri J Med Sci"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfi215"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2013.11.039"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S65382"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1283218"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2019.07.060"}],"container-title":["Hemodialysis International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hdi.13151","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,12]],"date-time":"2024-07-12T03:40:54Z","timestamp":1720755654000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hdi.13151"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":32,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,7]]}},"alternative-id":["10.1111\/hdi.13151"],"URL":"https:\/\/doi.org\/10.1111\/hdi.13151","archive":["Portico"],"relation":{},"ISSN":["1492-7535","1542-4758"],"issn-type":[{"value":"1492-7535","type":"print"},{"value":"1542-4758","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"2023-06-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-20","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}