{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:51:53Z","timestamp":1787014313711,"version":"build-2736575974"},"reference-count":33,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,3,23]],"date-time":"2025-03-23T00:00:00Z","timestamp":1742688000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Hemodialysis International"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Pulmonary hypertension affects patients with hemodialysis\u2010dependent end\u2010stage kidney failure; however, the estimated prevalence varies greatly due to the underutilization of right heart catheterization and the evolving diagnostic criteria of pulmonary hypertension. Pulmonary hypertension in end\u2010stage kidney failure is often attributed to arteriovenous (AV) access; therefore, we hypothesized that patients with AV fistula\/graft would have a greater prevalence of pulmonary hypertension on right heart catheterization compared to those with central venous (CV) catheter accesses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this retrospective single\u2010center cohort study, we identified and randomly sampled patients from July 2012 to August 2022 receiving hemodialysis for \u2265\u20093\u2009months and who underwent right heart catheterization, using Current Procedural Terminology codes. Pulmonary hypertension was defined as mean pulmonary arterial pressure (mPAP) &gt;\u200920\u2009mmHg. Our primary outcome was the prevalence of pulmonary hypertension among patients with AV fistula\/graft versus CV hemodialysis access, tested with descriptive statistics. We evaluated survival as a secondary outcome using a Cox proportional hazards model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 3834 patient charts were extracted. Overall, 444 charts were randomly sampled, resulting in 137 subjects meeting the inclusion criteria. The mean age was 63.8\u2009\u00b1\u200910.5\u2009years, and 62% were male. The most common etiology of end\u2010stage kidney failure was diabetic kidney disease (57.7%). Eighty percent of end\u2010stage kidney failure patients had pulmonary hypertension; however, the type of hemodialysis access was not associated with pulmonary hypertension (85% CV catheter vs. 79.5% AV access,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.59). Patients with pulmonary hypertension had lower hemoglobin (9.6\u2009\u00b1\u20090.8 vs. 11.2\u2009\u00b1\u20091.3\u2009g\/dL,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001) and serum albumin (2.3\u2009\u00b1\u20090.9 vs. 3.4\u2009\u00b1\u20090.6\u2009g\/dL,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001) than those without pulmonary hypertension. Those with pulmonary hypertension had an increased risk of mortality (hazard ratio: 2.2, 95% confidence interval: 1.04\u20134.61;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.04).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our findings show a high burden of pulmonary hypertension among this heterogeneous cohort of end\u2010stage kidney failure patients, with no association between pulmonary hypertension and the type of hemodialysis access. This study highlights the need for prospective investigations incorporating current strategies for pulmonary hypertension diagnosis and treatment among the dialysis\u2010dependent population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hdi.13231","type":"journal-article","created":{"date-parts":[[2025,3,23]],"date-time":"2025-03-23T20:59:22Z","timestamp":1742763562000},"page":"335-345","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Associations Between Type of Hemodialysis Access and Pulmonary Hypertension: A Single\u2010Center Retrospective Cohort"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0510-8267","authenticated-orcid":false,"given":"Muhammad Umair","family":"Jahngir","sequence":"first","affiliation":[{"name":"Section of Nephrology, Hypertension and Kidney Transplantation Temple University Hospital  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"De Antonis","sequence":"additional","affiliation":[{"name":"Lewis Katz School of Medicine at Temple University  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rizwan","family":"Rabbani","sequence":"additional","affiliation":[{"name":"Thomas Jefferson University Hospital  Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Ashiq","sequence":"additional","affiliation":[{"name":"Hillcrest South Hospital  Tulsa Oklahoma USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajiya","family":"Fatima","sequence":"additional","affiliation":[{"name":"Faisalabad Medical University  Faisalabad Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rabia","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Dow International Medical College  Karachi Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avrum","family":"Gillespie","sequence":"additional","affiliation":[{"name":"Section of Nephrology, Hypertension and Kidney Transplantation Temple University Hospital  Philadelphia Pennsylvania 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End\u2010Stage Renal Disease in the United States \u201cIncidence Prevalence Patient Characteristics and Treatment Modalities Bethesda (MD): National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases; 2023 \u201d2023 https:\/\/usrds\u2010adr.niddk.nih.gov\/2023\/end\u2010stage\u2010renal\u2010disease\/1\u2010incidence\u2010prevalence\u2010patient\u2010characteristics\u2010and\u2010treatment\u2010modalities."}],"container-title":["Hemodialysis International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hdi.13231","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T04:41:06Z","timestamp":1760503266000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hdi.13231"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,23]]},"references-count":33,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1111\/hdi.13231"],"URL":"https:\/\/doi.org\/10.1111\/hdi.13231","archive":["Portico"],"relation":{},"ISSN":["1492-7535","1542-4758"],"issn-type":[{"value":"1492-7535","type":"print"},{"value":"1542-4758","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,23]]},"assertion":[{"value":"2025-01-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}