{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T11:20:11Z","timestamp":1790162411210,"version":"4.1.0"},"reference-count":22,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T00:00:00Z","timestamp":1747785600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,5,21]],"date-time":"2025-05-21T00:00:00Z","timestamp":1747785600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Hemodialysis International"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Uncuffed, non\u2010tunneled dual\u2010lumen catheters are often required for kidney replacement therapy (KRT), but catheter\u2010related bloodstream infections (CRBSIs) remain a serious complication. Whether the jugular site poses a lower CRBSI risk than the femoral site is unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective cohort study analyzed patients with uncuffed, non\u2010tunneled dual\u2010lumen catheters. CRBSI incidence, catheter dwelling time, and mortality rates were compared between jugular and femoral sites. Regression analyses identified CRBSI risk factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 572 patients were included in the study. The incidence proportion of CRBSI was 3.5% in both the femoral and jugular groups (10 of 286 patients in each group;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20091.0). The incidence rates of CRBSI were 1.7 and 0.9 per 1000 patient\u2010days for the femoral and jugular sites, respectively (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.154). The median catheter dwelling time was significantly longer for jugular catheters (25\u2009days) compared to femoral catheters (12\u2009days;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). The 30\u2010day incidence proportion of death at the jugular site was significantly lower than at the femoral site (0.105 vs. 0.608,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Pre\u2010existing cerebrovascular disease and congestive heart failure were identified as significant risk factors for CRBSI.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>For uncuffed, non\u2010tunneled dual\u2010lumen catheters used for dialysis vascular access, the jugular insertion site does not demonstrate a reduced risk of CRBSI compared to the femoral site. However, jugular catheter placement is associated with a longer dwelling time and a lower mortality rate.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hdi.13261","type":"journal-article","created":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T00:14:44Z","timestamp":1747872884000},"page":"557-564","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Catheter\u2010Related Infection in Uncuffed, Non\u2010Tunneled Dual\u2010Lumen Catheters: Incidence and Risk Factors by Internal Jugular Versus Femoral Site in a Retrospective Cohort"],"prefix":"10.1111","volume":"29","author":[{"given":"Tanwaporn","family":"Phatpituk","sequence":"first","affiliation":[{"name":"Division of Nephrology, Department of Internal Medicine, Faculty of Medicine Thammasat University  Pathumthani Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2028-5037","authenticated-orcid":false,"given":"Suthiya","family":"Anumas","sequence":"additional","affiliation":[{"name":"Chulabhorn International College of Medicine Thammasat University  Pathumthani Thailand"},{"name":"60th Anniversary HRH Maha Chakri Sirindhorn Hemodialysis Center, Thammasat University Hospital  Pathumthani Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8087-7328","authenticated-orcid":false,"given":"Aphichat","family":"Chatkrailert","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Internal Medicine, Faculty of Medicine Thammasat University  Pathumthani Thailand"},{"name":"60th Anniversary HRH Maha Chakri Sirindhorn Hemodialysis Center, Thammasat University Hospital  Pathumthani Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,5,21]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kisu.2021.11.003"},{"key":"e_1_2_10_3_1","volume-title":"Thailand Renal Replacement Therapy: Year 2020","author":"Chuasuwan A.","year":"2020"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41581-018-0052-0"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2019.10.010"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2019.12.001"},{"key":"e_1_2_10_7_1","doi-asserted-by":"crossref","DOI":"10.1007\/978-981-16-9929-0","volume-title":"Onco\u2010Critical Care: An Evidence\u2010Based Approach","author":"Kumar V.","year":"2022"},{"key":"e_1_2_10_8_1","unstructured":"Z. Y.Bo Y.Wang D.Shi Q.Wang S.Xu andZ.Cao \u201cThe Incidence Rate and Economic Burden of Catheter\u2010Related Bloodstream Infection (CRBSI): A Single Center Retrospective Study \u201d2022 https:\/\/www.researchsquare.com\/article\/rs\u20101334417\/v2."},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.36864\/jinasvs.2021.1.009"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(04)01078-9"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13756\u2010020\u201000851\u20101"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/cc3824"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2000.00439.x"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0299715"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.06570711"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201303-0460OC"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.299.20.2413"},{"key":"e_1_2_10_18_1","first-page":"138","article-title":"A Study on Catheter Related Bloodstream Infections (CRBSI) in Intensive Care Unit Patients in a Tertiary Care Hospital","volume":"4","author":"Abirami E.","year":"2017","journal-title":"Indian Journal of Microbiology Research"},{"key":"e_1_2_10_19_1","first-page":"S93","article-title":"Microbiology, Risk Factors and Mortality of Patients With Intravenous Catheter Related Blood Stream Infections in the Surgical Intensive Care Unit: A Five\u2010Year, Concurrent, Case\u2010Controlled Study","volume":"97","author":"Cheewinmethasiri J.","year":"2014","journal-title":"Journal of the Medical Association of Thailand"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.3889\/oamjms.2022.7464"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.07710713"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.286.6.700"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2005.06.007"}],"container-title":["Hemodialysis International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hdi.13261","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/hdi.13261","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hdi.13261","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T01:31:23Z","timestamp":1773192683000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hdi.13261"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,21]]},"references-count":22,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10.1111\/hdi.13261"],"URL":"https:\/\/doi.org\/10.1111\/hdi.13261","archive":["Portico"],"relation":{},"ISSN":["1492-7535","1542-4758"],"issn-type":[{"value":"1492-7535","type":"print"},{"value":"1542-4758","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,21]]},"assertion":[{"value":"2025-01-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-05-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}